2003
DOI: 10.1590/s1677-04202003000100002
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Abstract: Lysine is an essential amino acid, synthesized in plants in the aspartic acid pathway. The lysine catabolism is performed by the action of two consecutive enzymes, lysine 2-oxoglutarate reductase (LOR) and saccharopine dehydrogenase (SDH). The steady state of lysine is controlled by both, synthesis and catabolism rates, with the final soluble lysine concentration in cereal seeds a direct result of these processes. In the last 40 years, the enzymes involved in lysine biosynthesis have been purified and characte… Show more

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Cited by 20 publications
(14 citation statements)
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References 55 publications
(14 reference statements)
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“…The degradation of lysine plays a pivotal role in the proper functioning of the mammalian brain by synthesizing glutamate, which regulates signals of nerve transmission through glutamate receptors 42 . In response to various environmental changes and stress conditions, lysine catabolizes into glutamate and affects the growth, development, and other physiological processes in the plant body 43 . Presence of lysine in R. billardieri helps this species to grow successfully in exposed and brightly lit conditions.…”
Section: Fig 2: Hplc Chromatogram Of Riccia Billardieri Fig 3: Hplcmentioning
confidence: 99%
“…DHDPS, the first enzyme directly involved in lysine biosynthesis, is strongly regulated by feedback inhibition by low concentrations of this amino acid and consequently plays the most important role in the regulation of lysine biosynthesis (17,28,29). DHDPS catalyzes the condensation of pyruvate and aspartate semialdehyde to dihydrodipicolinic acid, and has been purified and characterized in plants, exhibiting a molecular mass of 115 to 167 kDa (15,17).…”
Section: The Key Enzymes Involved In Lysine Metabolismmentioning
confidence: 99%
“…Essential amino acids like lysine and threonine are particularly important in cereal crops, due to the low concentration in the seeds (Fornazier et al, 2003). These amino acids, plus methionine and isoleucine have a common precursor, aspartate (Azevedo and Lea, 2001).…”
Section: Introductionmentioning
confidence: 99%
“…Alguns estudos cinéticos têm revelado resultados diversos. Em milho, a sacaropina é um inibidor competitivo de lisina e não-competitivo de cetoglutarato, sugerindo um mecanismo em que a lisina inicialmente interage com a enzima e depois com cetoglutarato e NADPH, sendo o oposto observado em arroz (FORNAZIER et al, 2003). Alguns estudos têm demonstrado em diferentes espécies que o aminoácido lisina pode regular seu próprio catabolismo com as enzimas sendo moduladas diferencialmente em uma cascata de sinais intracelular envolvendo principalmente cálcio e um processo de fosforilação-desfosforilação da proteína .…”
Section: O Catabolismo De Lisinaunclassified
“…A Lisina, produzida nas plantas através da via do ácido aspártico. Relatos recentes revelaram que a degradação da lisina pode estar relacionada com vários processos fisiológicos, por exemplo, crescimento, desenvolvimento e respostas às mudanças ambientais e estresses (FORNAZIER et al, 2003). E a Treonina, atua como promotora do crescimento (NELSON E COX, 2005…”
Section: Sacarose Sintaseunclassified