Lymphomatoid granulomatosis of the skin and lung. An angiocentric T-cell-rich B-cell lymphoproliferative disorder

Unusual case of subcutaneous panniculitis‐like T‐cell lymphoma

“…B cell monoclonality is usually demonstrated on PCR analysis of biopsy specimens. 17 While our case demonstrated some features of LG, the overall clinical, morphological and molecular biology results were more in keeping with SPTCL. Extranodal NK-cell and T-cell lymphomas of the nasal type can have many of the same features as SPTCL, including extensive involvement of the subcutaneous tissue, panniculitis-like morphological appearance 18 and an association with the HPS.…”

EBV-Negative Cutaneous Lymphomatoid Granulomatosis With Concomitant EBV-Positive Pulmonary Involvement

“…11,[17][18][19][20][21] In these studies, up to 50% of the cutaneous lesions failed to demonstrate EBER. Thus, the presence or absence of EBER in cutaneous lesions has not proven useful in grading or predicting the course of disease.…”

Rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis

“…[ 13 ] This case was initially thought to be of T-cell phenotype, but recent papers have shown that PLG is an EBV-positive B-cell proliferation associated with an exuberant T-cell response. [ 1 , 14 ] This unusual disease is adversely affected by the uncommon complication of intercurrent tuberculosis. [ 15 , 16 ] The type 1 helper T lymphocyte (Th1) response, capable of synthesizing interferon gamma (IFN-γ) and other cytokines, contains M. tuberculosis in a latent state without active replication.…”