2005
DOI: 10.1590/s0074-02762005000900018
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Abstract: Edema is a consistent observation in inflamatory bowel disease (IBD)

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Cited by 21 publications
(23 citation statements)
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“…These changes might disturb lymphangion pumping, and combined with altered LEC barrier could severely impair resolution of inflammation. [68][69][70][71] Our results clearly show cytokines disturb LEC functions in both mouse and human LEC in vitro with differential responses of these two cell types to cytokines.…”
Section: Discussionmentioning
confidence: 57%
“…These changes might disturb lymphangion pumping, and combined with altered LEC barrier could severely impair resolution of inflammation. [68][69][70][71] Our results clearly show cytokines disturb LEC functions in both mouse and human LEC in vitro with differential responses of these two cell types to cytokines.…”
Section: Discussionmentioning
confidence: 57%
“…Rhythmic contraction of lymphatic vessels is one of the major mechanisms underlying functional activity of the lymphatic system [7]. Mediators play a key role in modulation of function of lymphatic vessels during inflammation [6,10].The family of short peptides containing glycine and proline (glyprolines) is characterized by a wide range of physiological activity. They maintain homeostasis in the gastric mucosa under ulcerogenic conditions, prevent microcirculatory disturbances [2], inhibit thrombus formation [8], and are involved in the regulation of vascular tone [1].…”
mentioning
confidence: 99%
“…Rhythmic contraction of lymphatic vessels is one of the major mechanisms underlying functional activity of the lymphatic system [7]. Mediators play a key role in modulation of function of lymphatic vessels during inflammation [6,10].…”
mentioning
confidence: 99%
“…Despite several later descriptions regarding the edema and the dilation of lymphatic vessels in the intestinal wall of CD, only a few studies have focused about the role of lymphatics in this disorder [13,17,19,20].…”
Section: Discussionmentioning
confidence: 99%
“…Several hypotheses can be made regarding possible mechanisms for lymphedema in CD, including congenital agenesia, obstruction, or alterations in the course of lymphatic drainage in the mesentery [9,19,20]. It is well known that different genes control the development of lymphatics.…”
Section: Discussionmentioning
confidence: 99%