Lyme borreliosis in dogs and humans in the USA

Little, Susan E.; Heise, S.; Blagburn, Byron L.; Callister, Steven M.; Mead, Paul S.

doi:10.1016/j.pt.2010.01.006

Cited by 79 publications

(69 citation statements)

References 52 publications

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“…Because of their outdoor activities and body fur, dogs are generally at higher risk of tick bites and tick-borne diseases than humans (1). Immunoassays of serum samples from pet dogs revealed positive correlations between the prevalence of antibodies to B. burgdorferi antigens and the distribution of I. scapularis (2,3).…”

mentioning

confidence: 99%

Diversity of Antibody Responses to Borrelia burgdorferi in Experimentally Infected Beagle Dogs

Baum

Grosenbaugh²,

Barbour

2014

Clin Vaccine Immunol

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mentioning

confidence: 99%

Diversity of Antibody Responses to Borrelia burgdorferi in Experimentally Infected Beagle Dogs

Baum

Grosenbaugh²,

Barbour

2014

Clin Vaccine Immunol

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“…Los habitantes de ambas comunidades rurales que trabajan en el campo y tienen acceso a áreas selváticas o agrícolas, podrían tener mayor riesgo de adquirir el agente, ya que pueden tener mayor exposición a garrapatas infectadas con las espiroquetas (Stanek, Wormser, Gray, & Strle, 2012 Actualmente, la borreliosis canina en México es poco estudiada, debido a que los perros infectados con Borrelia spp. generalmente no desarrollan signos clínicos asociados con esta espiroqueta, los que hace más difícil su detección, monitoreo y tratamiento (Little et al, 2010). Sin embargo, en algunas ocasiones los perros infectados con la bacteria pueden presentar artritis migratoria, claudicación intermitente, anorexia y malestar general.…”

Section: Discussionunclassified

“…(Ogden et al, 2006;Solís-Hernández et al, 2015). La detección de Borrelia en perros podría ser un criterio importante para la evaluación del riesgo de la EL en humanos, ya que el perro puede emplearse como indicador epidemiológico para la identificación de nuevos focos de esta enfermedad (Bhide, Travnicek, Curlik, & Stefancikova, 2004;Little, Heise, Blagburn, Callister, & MeadLyme, 2010).…”

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Detección de Borrelia burgdorferi sensu lato en perros y sus garrapatas en comunidades rurales de Yucatán, México

Solís-Hernández

Rodríguez-Vivas

Esteve-Gassent

et al. 2017

RBT

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In Mexico, the distribution and the presence of pathogenic genospecies of B. burgdorferi in dogs and their ticks has not been extensively investigated. The study of canine borreliosis is acquiring greater relevance, since the dog is considered to be an important sentinel for pathogens pertaining to the complex Borrelia burgdorferi sensu lato; in addition, dogs could be playing a key role in the spread of ticks from forested areas into the domestic environment. This study aimed to detect and estimate the prevalence of B. burgdorferi s.l. in dogs and their ticks in two rural communities of Yucatán, Mexico. In each community, 50 houses were visited, where 144 blood samples from dogs were studied by puncture of the saphenous vein, as well as the collection of their ticks. To detect the presence of B. burgdorferi s.l. in these samples, the conserved gene flaB, p66 and ospC were PCR amplified. A total of 144 dog blood samples, and 846 of ticks were obtained from the examined animals. Considering tick species, Rhipicephalus sanguineus sensu lato (786 / 846) was common, while Ixodes affinis (33 / 846), and Amblyomma mixtum (27 / 846) resulted less frequent. As per gene conservation, the prevalence of B. burgdorferi in canine blood was 17.3 % (25 / 144) to flaB, 12.50 % (18 / 144) for p66 and 1.38 % (2 / 144) for the ospC gene. Within the analyzed ticks, R. sanguineus s.l. had a prevalence of 0.89 %, A. mixtum 5.88 % and I. affinis 15.15 %, being this last species the one that presented higher prevalence. Two dogs and their ticks I. affinis were positive to the flaB gene. Only a tick R. sanguineus s.l. was positive to the gene p66 and no tick species was positive the ospC gene. This study confirmed the existence of B. burgdorferi s.l. in dogs and their ticks in rural communities of Yucatán, Mexico. The detection of Borrelia in dogs may be an important criterion for the evaluation of the risk of borreliosis in humans, since the dog can be used as an epidemiological indicator for the identification of new outbreaks of this disease.

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“…Similarly to what is observed in humans, these microorganisms can infect species of domestic animals and wildlife, and they are transmitted primarily by ticks (LITTLE et al, 2010). Various tick species have been described as parasitizing buffaloes (NITHIKATHKUL et al, 2002), which makes them possible hosts for the etiological agents transmitted by these arthropods.…”

Section: Introductionmentioning

confidence: 93%

Detection of anti-Borrelia burgdorferi antibodies in buffaloes (Bubalus bubalis) in the state of Pará, Brazil

Corrêa

Teixeira

Oliveira

et al. 2012

Rev. Bras. Parasitol. Vet.

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Detection of anti-Borrelia burgdorferi antibodies in buffaloes (Bubalus bubalis) in the state of Pará, Brazil AbstractThis study aimed to investigate the frequency of homologous antibodies of IgG class against Borrelia burgdorferi in buffaloes in the state of Pará, Brazil. Blood serum samples from 491 buffaloes were analyzed by means of the indirect ELISA test, using crude antigen produced from a cultivar of the North American strain G39/40 of B. burgdorferi. There were 412 positive samples (83.91%), and there was no statistically significant difference in the proportions of positive animals between the 81.69% (232/284) originating from Marajó Island and the 86.96% (180/207) from the continental area of the state of Pará. In all the municipalities studied, the frequency of positive findings of antibodies against B. burgdorferi among the animals ranged from 63.6% to 92.9%. The high numbers of seropositive animals can be explained by the frequent presence of the tick Rhipicephalus (Boophilus) microplus, and by the possible existence of spirochetes of the genus Borrelia infecting buffaloes in the region studied, although specific studies are needed to confirm this relationship. These factors suggest that a cross-reaction exists between the North American strain G39/40 of B. burgdorferi, which is used as an antigenic substrate, and the species of Borrelia spp. that possibly infects buffaloes in the state of Pará.Keywords: Buffaloes, Borrelia spp., epidemiology, serology. ResumoEste estudo teve como objetivo investigar a frequência de anticorpos homólogos da classe IgG contra Borrelia burgdorferi em búfalos do estado do Pará. Amostras de soro de 491 búfalos foram analisadas por meio do teste ELISA indireto, utilizando antígeno bruto produzido a partir do cultivo da cepa norte americana G39/40 de B. burgdorferi. Foram encontrados 412 soros positivos (83,91%), não havendo diferença estatística significativa entre os 81,69% (232/284) animais positivos provenientes da Ilha de Marajó e os 86,96% (180/207) da base continental do estado do Pará. Em todos os municípios estudados os animais apresentaram frequência de anticorpos contra B. burgdorferi, com positividade variando de 63,6% a 92,9%. O alto número de soropositivos pode ser explicado pela frequente presença do carrapato Rhipicephalus (Boophilus) microplus e pela possível existência de espiroquetas do gênero Borrelia infectando búfalo na região estudada, embora novos estudos sejam necessários para a confirmação desta relação. Estes fatos sugerem reação cruzada entre a cepa americana G39/40 de B. burgdorferi utilizada como substrato antigênico e a espécie de Borrelia spp. que possivelmente infecta bubalinos no estado do Pará.

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Lyme borreliosis in dogs and humans in the USA

Cited by 79 publications

References 52 publications

Diversity of Antibody Responses to Borrelia burgdorferi in Experimentally Infected Beagle Dogs

Diversity of Antibody Responses to Borrelia burgdorferi in Experimentally Infected Beagle Dogs

Detección de Borrelia burgdorferi sensu lato en perros y sus garrapatas en comunidades rurales de Yucatán, México

Detection of anti-Borrelia burgdorferi antibodies in buffaloes (Bubalus bubalis) in the state of Pará, Brazil

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