Lupus Erythematosus Profundus

Ocular Manifestations of Systemic Lupus Erythematosus: A Review of the Literature

“…Subcutaneous inflammation secondary to SLE was first described by Kaposi in 1883, and the term “lupus erythematosus panniculitis” was coined in 1940 [14]. It is most commonly encountered in the setting of discoid lupus erythematosus.…”

Membranous lipodystrophy

“…Differential diagnosis of ML is not easy, because these peculiar changes in fat tissue have been associated with other local and systemic diseases including lupus erythematosus, eythema nodosum, fat tissue granuloma, hemodialysis patients with carpal tunnel syndrome, progressive systemic sclerosis, diabetes mellitus, cases of limb ischemic necrosis caused by arteriosclerotic obstruction, thromboamgiitis obliterans, statis dermatitis, etc. [26][27][28][29][30][31].…”

Dapsone-induced Haemolysis

“…The two statements would be compatible if Goodman and Gilman had said " haemolysis " instead of " haemolytic anaemia," for a considerable degree of haemolysis has to occur to cause actual anaemia, provided that the bone-marrow function is not impaired (Crosby and Dameshek, 1955). Frank anaemia must be rare in dapsonetreated patients, for it is not even mentioned in a report about 10,000 lepers receiving the drug (Garrett and Corcos, 1952), though anaemia of unspecified type has been recognized (Allday and Barnes, 1951;Lowe and Davey, 1951;Dharmendra and Chatterji, 1953;Gilbert, 1953;Kruizinga and Hamminga, 1953;Alexander, 1955;Morgan et al, 1955;Garrett, 1956) and sometimes evidence of haemolysis (Lowe, 1950;Ramanujam andSmith, 1951: Smith andAlexander, 1959;Arnold, 1962). Smith and Alexander (1959) noted Heinz bodies in the red cells of four patients taking 100 to 200 mg. of dapsone daily.…”