Lupus Erythematosus

Use of Vitamins and their Derivates in the Treatment of Cutaneous Disorders

“…Several authors reported the satisfactory use of vitamin E as co-adjuvant in various inflammatory conditions of the skin such as discoid lupus erythematosus and lichen sclerosus et atrophicus [195][196][197][198][199].…”

Toxicological Aspects of Antioxidants Used as Food Additives

“…These occurred only at intakes of 500-2000 mg daily and were transient or disappeared on cessation of treatment. [82][83][84][85][86] Two reports have indicated the possible susceptibility of premature infants to adverse effects when vitamin E is given therapeutically to prevent retrolental fibroplasia, haemolysis and haemorrhage, at doses which maintain supra-physiological serum levels of vitamin E. There was an increased incidence of neonatal sepsis and necrotising enterocolitis following oral or parenteral administration of vitamin E preparations. 87 An intravenous vitamin E product caused a syndrome of pulmonary deterioration, thrombocytopenia, liver failure and renal failure.…”