Lupus-Associated Chorea in Childhood

Abstract

\s=b\Chorea associated with systemic lupus erythematosus (SLE) has been reported in only 28 patients. The clinical and laboratory features of these cases are reviewed here, along with those of a 7-year-old boy who, we believe, represents the youngest child reported to date. In approximately half of these 29 individuals, most of whom were children, chorea preceded other manifestations of SLE. The age range and clinical characteristics of lupus-associated chorea were not appreciably different from those of Sydenham's chorea and most of the patients in whom chorea developed before other manifestations of SLE were initially assumed to have Sydenham's chorea. Systemic lupus erythematosus should especially be considered if chorea begins in the older child or is associated with a persistently elevated erythrocyte sedimentation rate.

Movimentos involuntários anormais como primeira manifestação do lupus eritematoso sistêmico: relato de caso

“…Em 28 casos de associação de coréia com LES estudados por Groothuis e col. 15 , 75% dos pacientes tinham menos de 16 anos e 91% tinham menos de 20 anos.…”

The Clinical Presentation of Systemic Lupus Erythematosus

“…Even though movement disorders are not common in lupus, chorea is common in children with SLE and is found in adults and children with phospholipid antibody [81]. It is virtually indistinguishable from Sydenham chorea.…”

The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes

“…Chorea is the most common movement disorder observed in SLE, particularly in children (99)(100)(101), whereas reports on Parkinson's disease and hemiballismus are rare. Chorea is the most common movement disorder observed in SLE, particularly in children (99)(100)(101), whereas reports on Parkinson's disease and hemiballismus are rare.…”