Lupin kernel fibre-enriched foods beneficially modify serum lipids in men

Abstract

Objective: To examine the effect of a diet containing a novel legume food ingredient, Australian sweet lupin (Lupinus angustifolius) kernel fibre (LKFibre), compared to a control diet without the addition of LKFibre, on serum lipids in men. Design: Randomized crossover dietary intervention study. Setting: Melbourne, Australia -Free-living men. Subjects: A total of 38 healthy males between the ages of 24 and 64 y completed the intervention. Intervention: Subjects consumed an LKFibre and a control diet for 1 month each. Both diets had the same background menus with seven additional experimental foods that either contained LKFibre or did not. Depending on energy intake, the LKFibre diet was designed to contain an additional 17 to 30 g/day fibre beyond that of the control diet. Results: Compared to the control diet, the LKFibre diet reduced total cholesterol (TC) (mean7s.e.m.; 4.571.7%; P ¼ 0.001), low-density lipoprotein cholesterol (LDL-C) (5.472.2%; P ¼ 0.001), TC: high-density lipoprotein cholesterol (HDL-C) (3.072.0%; P ¼ 0.006) and LDL-C:HDL-C (3.872.6%; P ¼ 0.003). No effects on HDL-C, triacylglycerols, glucose or insulin were observed. Conclusions: Addition of LKFibre to the diet provided favourable changes to some serum lipid measures in men, which, combined with its high palatability, suggest this novel ingredient may be useful in the dietary reduction of coronary heart disease risk.

Effects of increasing dietary protein and fibre intake with lupin on body weight and composition and blood lipids in overweight men and women

“…Isolation and purification of lupin kernel fibre can result in a higher ratio of soluble to insoluble fibre and higher viscosity and water-binding capacity than fibre naturally present in LKF. 46 In addition, the increase in lupin kernel fibre intake in the study by Hall et al 25 was about twice of that in our study.…”

“…24 In humans, a lupin fibre isolate, providing an additional 17-30 g per day of dietary fibre, reduced total and low-density lipoprotein (LDL)-cholesterol concentrations by B5%. 25 Results of acute studies also suggest the potential for benefit of lupin-enriched foods on blood glucose metabolism. 2,26 We have previously shown that consumption of LKF-enriched bread significantly reduced postprandial glucose and insulin in comparison with matching energy from white bread.…”

“…A previous study 25 showed that a 17-30 g increase in fibre intake from isolated lupin kernel fibre significantly reduced Lupin, body weight and blood lipids JM Hodgson et al total cholesterol and LDL-cholesterol by B5% in healthy men. Another possible explanation for the seemingly inconsistent findings is that the increased fibre intake in our study was achieved through the incorporation of LKF-enriched bread into the daily diet rather than an isolated fibre.…”

“…Another possible explanation for the seemingly inconsistent findings is that the increased fibre intake in our study was achieved through the incorporation of LKF-enriched bread into the daily diet rather than an isolated fibre. 25 The process of isolation of the lupin kernel fibre may have altered its properties or concentrated a more bioactive fraction. Isolation and purification of lupin kernel fibre can result in a higher ratio of soluble to insoluble fibre and higher viscosity and water-binding capacity than fibre naturally present in LKF.…”

The health benefits of sweet lupin seed flours and isolated proteins

“…Both studies produced significant decreases of total and LDL-C, but the changes were much less favourable in the old study (R. S. Hall, Johnson, Baxter, & Ball, 2005), where the changes in total cholesterol and LDL-C were -0.22 mmol/L and -0.19 mmol/L, respectively, than in the recent one based on subjects with higher baseline cholesterol levels , where the changes in total cholesterol and LDL-C were -0.42 mmol/L and -0.33 mmol/L, respectively. In the latter study, a significant decrease of blood pressure was also observed (section 4.2.)…”