2011
DOI: 10.1055/s-0030-1250240 View full text |Buy / Rent full text
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Abstract: Immunosuppressed patients are at an increased risk for severe disease from influenza A (H1N1). We report a case of a patient who died of septic complications from H1N1 acquired at the time of single lung transplant.

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“…5 Mason et al reported a case of a lung transplant recipient who died of septic complications from H1N1. 3 Therefore, screening for bacterial and fungal pathogens should continue after the initiation of antiviral therapy and potent antibiotic and antifungal medications should be liberally started. Prevention of H1N1 infection by vaccination in solid organ transplant recipients is recommended by a majority of studies despite varying efficacies.…”
Section: Discussionmentioning
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“…5 Mason et al reported a case of a lung transplant recipient who died of septic complications from H1N1. 3 Therefore, screening for bacterial and fungal pathogens should continue after the initiation of antiviral therapy and potent antibiotic and antifungal medications should be liberally started. Prevention of H1N1 infection by vaccination in solid organ transplant recipients is recommended by a majority of studies despite varying efficacies.…”
Section: Discussionmentioning
“…An antiviral therapy with oral oseltamivir 75 mg twice a day was initiated as recommended. 3 During the course of hospitalization her clinical condition worsened. She developed increasing dyspnea and her temperature rose to 37.9°C.…”
Section: Case Presentationmentioning
“…Experience with H1N1 showed that lung transplant patients are at high risk of mortality during pandemics. 35 Furthermore, during a surge there may be a scarcity of resources required to support the prolonged post-operative care of a transplant patient. If transplant is performed, patients must not be actively infected with SARS-CoV-2, at least 14 days after initial diagnosis and recipients should have 2 negative PCR-based tests at least 48 h apart prior to transplantation.…”
Section: Perioperative Considerationsmentioning
“…This situation was found to be true for a patient who showed a rapid onset of fever and a concomitant sepsis syndrome; the patient succumbed to septic H1N1 complications after oseltamivir and later peramivir treatment. Of interest, H1N1 cultures were negative from the graft, yet positive for the initial nasopharyngeal swab [35]. In contrast, perioperative infection and subsequently successful treatment of H1N1 infection (with oseltamivir and zanamivir) were reported for a 19-year-old woman with Burkholderia-negative cystic fibrosis who underwent double lung transplantation.…”
Section: Other Viral Pathogens In Lung Transplant Recipientsmentioning