2019
DOI: 10.1097/mot.0000000000000627
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Abstract: PURPOSE OF REVIEW The current review presents a concise update on published literature on donation after circulatory death (DCD) and lung transplantation (LTx). Worldwide an increasing need for lungs is evident, however the utilization rate of DCD lung donors is still considerably low. In this summary article, we reviewed both the experimental background and international clinical experience. RECENT FINDINGS Our analysis confirmed satisfactory results for LTx from DCD donors, which equals the results from dona… Show more

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Cited by 31 publications
(24 citation statements)
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“…Several series from individual institutions and national organizations have now reported comparable early-and medium-term recipient outcomes after lung transplantation from cDCDD versus standard DNDD donors [72]. The largest experience with cDCDD comes from the DCDD Registry by the International Society for Heart and Lung Transplantation (ISHLT) with 22 participating institutions worldwide.…”
Section: Ex Situ Lung Perfusion and Repairmentioning
confidence: 99%
“…Several series from individual institutions and national organizations have now reported comparable early-and medium-term recipient outcomes after lung transplantation from cDCDD versus standard DNDD donors [72]. The largest experience with cDCDD comes from the DCDD Registry by the International Society for Heart and Lung Transplantation (ISHLT) with 22 participating institutions worldwide.…”
Section: Ex Situ Lung Perfusion and Repairmentioning
confidence: 99%
“…This study demonstrated the simplicity, safety, and the potential of recovering lungs from uncontrolled DCDs. Lung inflation with continuous positive airway pressure followed by ventilation and cold flush are simple measures for lung protection in uncontrolled DCDs when compared to other techniques previously reported by lung transplant groups in Sweden, Spain, and Italy using topical cooling via chest drains or continued cardiac massage to restore pulmonary circulation 4,5 . However, even with these simple measures, the logistical burden on the organ donation organization and on the donor team is considerable while the utilization rate (≈15%) remains low.…”
Section: Figurementioning
confidence: 99%
“…Nevertheless, EVLP could select out the best lungs, reducing the recipient's risk of developing severe primary graft dysfunction (PGD) after transplantation. This situation differs compared to the setting of controlled DCDs whereby EVLP as an assessment tool is rarely needed in cases with a short agonal phase after withdrawal of life‐sustaining therapy and with a total warm ischemic time limited to 30 minutes prior to cold preservation 5 . Early outcome in these 5 recipients in Toronto was excellent, with no PGD grade 3 up to 72 hours in any recipient and no mortality at 30 days.…”
Section: Figurementioning
confidence: 99%
“…Other European countries, such as Spain and Austria, which have adopted the concept of presumed consent, achieved donation rates as high as 46.9 pmp in Spain and 23.5 pmp in Austria in 2017 [48,49]. Donation after cardiocirculatory-determined death has been shown to achieve successful results in transplantation of organs such as kidneys, livers and lungs [50][51][52][53]. In recent years, DCD programs have also been established in heart transplantation.…”
Section: Current Aspects Of Heart Transplantationmentioning
confidence: 99%