&lt;title&gt;Intraoral fiber-optic-based diagnostic for periodontal disease&lt;/title&gt;

Colston, Bill W.; Gutierrez, Dora M.; Everett, Matthew J.; Brown, Steve B.; Langry, Kevin C.; Cox, W. Royall; Johnson, Paul W.; Roe, Jeffrey N.

doi:10.1117/12.384906

Cited by 6 publications

(2 citation statements)

References 14 publications

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“…Chemical sensor materials can be ink-jet printed onto detectors for use in clinical diagnosis, 35 manufacturing process control, environmental monitoring, etc. UV-curing epoxies can be modified to be porous and doped with chemical indicators.…”

Section: Protein and Dna Depositionmentioning

confidence: 99%

Applicatons of Ink-Jet Printing Technology to BioMEMS and Microfluidic Systems

Cooley¹,

Wallace²,

Antohe³

2002

JALA: Journal of the Association for Laboratory Automation

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Applications of microfluidics and MEMS (micro-electromechanical systems) technology are emerging in many areas of biological and life sciences. Non-contact microdispensing systems for accurate, high-throughput deposition of bioactive fluids can be an enabling technology for these applications. In addition to bioactive fluid dispensing, ink-jet based microdispensing allows integration of features (electronic, photonic, sensing, structural, etc.) that are not possible, or very difficult, with traditional photolithographic-based MEMS fabrication methods. Our single fluid and multifluid (MatrixJet™) piezoelectric microdispensers have been used for spot synthesis of peptides, production of microspheres to deliver drugs/biological materials, microprinting of biodegradable polymers for cell proliferation in tissue engineering applications, and spot deposition for DNA, diagnostic immunoassay, antibody and protein arrays. We have created optical elements, sensors, and electrical interconnects by microdeposition of polymers and metal alloys. We have also demonstrated the integration of a reversed phase microcolumn within a piezoelectric dispenser for use in the fractionation of peptides for mass spectrometer analysis.

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Section: Protein and Dna Depositionmentioning

confidence: 99%

Applicatons of Ink-Jet Printing Technology to BioMEMS and Microfluidic Systems

Cooley¹,

Wallace²,

Antohe³

2002

JALA: Journal of the Association for Laboratory Automation

View full text Add to dashboard Cite

show abstract

“…In 2000 Colston et al [138] developed a diagnostic device to permit simultaneous quantitation of multiple proteases within a single periodontal pocket, using a chemical fiber optic sensor, for the diagnosis of periodontal disease. Recent efforts were made to push forward further investigation to permit the use of FBG in in vivo studies, to perform strain measurements in bones, and that the osteoblastic biocompatibility be evaluated [139].…”

Section: Other Applicationsmentioning

confidence: 99%