<p>The Impact of Direct-to-Consumer Pharmaceutical Advertising on Public Knowledge of Gastroesophageal Reflux Disease: A Study on Over-the-Counter Proton Pump Inhibitors</p>

Abstract

Background: The use of direct-to-consumer advertising (DTCA) to promote sales of overthe-counter (OTC) pharmaceuticals used to manage common medical conditions, such as gastroesophageal reflux disease (GERD), is increasing. However, the educational value of these advertisements as well as the public perceptions of this type of advertising remain largely unknown among non-English speaking populations. Objective: The aim of this study was to explore the public perceptions and educational value of a short motion graphic video documenting the lifestyle of person with GERD and presenting a brief introduction to the role of proton pump Inhibitors (PPIs) in relieving the symptoms. Methods: This was a prospective quasi-experimental study in which a short mock advertising motion graphic video was shown to a sample of adult individuals in malls and shopping centers in different cities across Saudi Arabia. Participants were required to express their levels of agreement with six statements concerning their perceptions of DTCA of OTC drugs, and answer a quiz consisting of three questions and enquiries about their knowledge of GERD and the OTC drugs used in its treatment. Results: Two hundred and ninety-five participants were involved in this study, the majority of whom were female (55.30%). After watching the video, the percentages of participants who strongly agreed or agreed that DTCA is a credible source of information and encourages them to purchase the marketed drug have increased significantly (P<0.05). With regard to the quiz, the percentages of participants with correct answers regarding the definition of GERD, knowledge of OTC drugs for GERD, and awareness of the common side effects of PPIs increased from 81.69% to 95.93%, 69.83% to 96.27%, and 46.44% to 91.53%, respectively (P<0.0001). Conclusion: DTCA of OTC drugs for GERD, particularly if the content complies with the regulatory requirements, can promote the public knowledge of the disease and treatment options.

Layperson Perception of Reflux‐Related Symptoms

“…These patients demonstrated a 15% increase in correct answers regarding the definition of GERD, 25% increase in knowledge of available medications for GERD, and 45% increase in knowledge of side effects of proton pump inhibitors. 26 The current analysis found significant differences between clinician and patients on many definitions of what constitutes "reflux" and emphasizes the importance of careful history taking and patient education in clinic. Most patients and clinicians tended to agree that stomach-related symptoms were highly associated with reflux, but patients were much less likely to attribute extraesophageal symptoms, or symptoms within the chest, throat, and sensory domains, as related to reflux.…”

“…One study evaluated the impact of DCTA advertising on public knowledge of GERD, during which a mock advertisement about GERD and proton pump inhibitors was shown to participants in public venues. These patients demonstrated a 15% increase in correct answers regarding the definition of GERD, 25% increase in knowledge of available medications for GERD, and 45% increase in knowledge of side effects of proton pump inhibitors 26 …”

“…These patients demonstrated a 15% increase in correct answers regarding the definition of GERD, 25% increase in knowledge of available medications for GERD, and 45% increase in knowledge of side effects of proton pump inhibitors. 26 …”

Self-medication among adults with chronic health conditions: a population-based cross-sectional survey in Saudi Arabia

“…People with higher educational levels are more able to comprehend the patient information pamphlets and might feel more confident in using medications for self-medicating in comparison to their counterparts with lower educational levels. With regard to the higher rate of SM among women, this can be related to multiple factors, such as their previous experiences with different medications and herbal products in treating different minor illnesses among their kids or other family members, and their tendency to be influenced more by direct-to-consumer drug and herbal products advertisements 10 24 29…”

Assessment of Awareness and Knowledge of Proton Pump Inhibitors Among the General Population in the Qassim Region, Saudi Arabia

“…Another study by Alasmari et al [25] focused on physicians, pharmacists, and clinical pharmacists in Saudi Arabia, revealing significant disparities in PPI awareness, with more reporting poor knowledge. AlShammari et al [26] studied adults in Saudi Arabian malls, assessing over-the-counter PPI usage. Initially, low knowledge and awareness improved through pharmaceutical advertising, enhancing public understanding of gastroesophageal reflux disease.…”