<p>Performance and Safety of the Extended Depth of Focus Implantable Collamer^® Lens (EDOF ICL) in Phakic Subjects with Presbyopia</p>

Abstract

Purpose To evaluate the performance and safety of the Extended Depth of Focus Implantable Collamer ® Lens (EDOF ICL) for improvement of uncorrected near, intermediate and distance visual acuity in phakic subjects with myopia and presbyopia. Design Prospective multicenter study. Methods Presbyopic subjects who required an EDOF ICL in the range of −0.50 D to −18.00 D, exhibited ≤ 0.75 D refractive astigmatism and required from +1.00 to +2.50 D reading add were implanted bilaterally. Assessments at 6 months included uncorrected near, intermediate and distance visual acuities, defocus curves, contrast sensitivity, responses to the National Eye Institute Refractive Error Quality of Life Questionnaire and a Task Assessment Questionnaire. Results A total of 34 subjects completed the study. Investigators targeted emmetropia in all eyes. Mean binocular uncorrected near, intermediate and distance visual acuities measured logMAR −0.01 ± 0.05 (20/20), −0.02 ± 0.08 (20/19) and 0.07 ± 0.10 (20/23), respectively. Mean monocular uncorrected near, intermediate and distance visual acuities measured logMAR 0.068 ± 0.09 (20/23), 0.062 ± 0.10 (20/23) and 0.16 ± 0.12 (20/29). There were no clinically or statistically significant differences in contrast sensitivity between baseline and 6 months under any testing conditions. Subjects reported significant improvements in measures of vision-related quality of life and ability to perform tasks at all distances without glasses or contact lenses. Overall, satisfaction with the EDOF ICL was high: postoperatively, 91.2% of subjects were satisfied with their vision. Conclusion This multicenter, prospective clinical investigation demonstrated the ability of the EDOF ICL to correct myopia and presbyopia, resulting in improvement of uncorrected near, intermediate and distance visual acuity without compromising the quality of vision. The EDOF ICL allowed subjects to perform tasks of daily living without glasses or contact lenses. Subjects reported significant improvements in quality of life with high levels of spectacle independence and satisfaction.

Analysis of vault prediction in phakic implantable phakic collamer lenses: manufacturer’s calculator vs theoretical formulae vs clinical practice

“…Calculating ICL size is essential for the success of the surgery, as miscalculations can lead to complications such as cataract, angular closure, etc. According to the results reported by Parker (Packer, Alfonso et al 2020) in his work, there is still no definitive method for determining the size of the ICL, which is why it is considered necessary to analyse the current formulas available and compare them with clinical outcomes. In another literature review recently published, Montés-Micó et al concluded that anterior segment anatomy should be carefully studied to obtain good results and avoid complications (Ando, Kamiya et al 2020, Montés-Micó, Ruiz-Mesa et al 2021).…”

Effectiveness of SMILE Combined with Micro-Monovision in Presbyopic Patients: A Pilot Study

“…Moreover, special formulas for post-laser refractive surgery such as those included in the ASCRS online calculator ( accessed on 16 March 2023), thick-lens or ray-tracing formulas should be used [ 33 , 34 ]. Presbyopic phakic IOLs could also be an alternative for those patients, but CSDC studies are still required to determine if CS is also maintained along the whole defocus range [ 35 , 36 , 37 ].…”

Ten-year outcomes of pseudophakic mini-monovision correction of hyperopic presbyopia

“…A surgical correction of presbyopia may consist of a cornea surgery (using excimer and femtosecond laser procedures for creating monovision or multifocality, intrastromal radial segments, or corneal inlays) or intraocular lens (IOL) implantation (both with pseudophakic IOLs or, more recently, with phakic IOLs). [1][2][3][4] The pseudophakic correction of presbyopia consists of implantation of various IOLs after the patient's crystalline lens extraction (either clear lens extraction or cataract surgery). There are a rapidly growing number of pseudophakic IOLs available on the market, which are broadly categorized as "standard monofocal," multifocal diffractive, multifocal refractive, and extended depth of focus IOLs.…”