<p>Correlation between body mass index and ocular parameters</p>

Abstract

Purpose: To investigate the relationship between BMI and selected ocular parameters. Subjects and methods: Fifty-three left eyes of normal weight subjects and 67 age-sex matched overweight subjects were studied. Inclusion criteria for the normal weight and overweight groups included BMI between 18.5–22.9 and 23.0–29.9 kg/m 2 , respectively. Subjects with a history of systemic disease, ocular disease or surgery, or disability were excluded. All subjects underwent a medical history interview, arterial blood pressure, height, weight, waist circumference and hip circumference measurements, and BMI and waist-hip ratio calculation. The intraocular pressure (IOP) and anterior corneal curvature were measured by non-contact tonometry and corneal topography, respectively. Measurement of anterior and posterior segment parameters of the eye, including central corneal thickness, anterior chamber depth (ACD), anterior chamber angle, macular thickness (MT), ganglion cell thickness (GCT), retinal nerve fiber layer thickness, cup to disc ratio, and choroidal thickness was performed by enhanced depth-imaging optical coherence tomography. Results: There was a positive correlation between ACD and BMI (Univariate analysis; β =0.198, P =0.030, Multivariate analysis; β =0.410, P =0.005) and between BMI and IOP (Univariate analysis; β =0.269, P =0.003). The IOP of the overweight group was found to be significantly higher than of the normal weight group (12.80±3.40 and 11.86±2.12 mm Hg, respectively, P =0.002). Also, there was a significant difference found between the GCT and the MT of the two groups ( P =0.036 and 0.009, respectively). Conclusion: It was found that BMI strongly correlated with ACD and IOP. Also, the degree of obesity was found to be a significant factor; therefore, the relationship between these ocular parameters and the severity of obesity should be further investigated.

Evaluation of the choroidal thickness and retinal nerve fiber layer and visual fields in morbid obesity

“…In addition to the studies indicating that the CT among obese subjects is not different from those of the normal population,[ 23 ] contrasting studies are postulating that CT is thinner in obese subjects. [ 8 9 24 ] CT measurements can be affected by many factors, such as age, gender, ethnicity, axial length, diurinal variations, and coffee and cigarette dependence, which may account for the differences between the studies.…”

Obese Foveal Avascular Zone Assessed by Optical Coherence Tomography Angiography of the Retina: Is There a Relation to Comorbities?

“…In the present study, no significant differences were found between the measurements taken of central macula thickness, subfoveal choroidal thickness, mean peripapillary retinal nerve fiber layer thickness, superior peripapillary retinal nerve fiber layer thickness, inferior peripapillary retinal nerve fiber layer thickness, nasal peripapillary retinal nerve fiber layer thickness and temporal peripapillary retinal nerve fiber layer thickness between the study group and the control group. It is interesting to note that there are studies that describe a decrease in the subfoveal choroidal thickness [9], a decrease in the thickness of the retinal nerve fiber layer [9] [11] and an increase in macular thickness [8] in obese individuals. It is possible that these findings are due to samples with different characteristics such as refractive errors, for example.…”

The Effects of Sex, Oral Contraception, and Menstrual Cycle Phase on Intraocular Pressure, Central Corneal Thickness, and Foveal Thickness: A Descriptive Analysis

“…All systemic parameters (BMI, BGL, SBP, and DBP) were significantly higher in men than in women, possibly mediating some of our sex differences in ocular biometrics. Our trends for higher IOP in men could have been due to higher BMI and BGL levels, which have both been found to positively correlate with IOP [ 25 , 28 ]. The role of BP in the regulation of IOP is complex, and some studies have shown that BP increases of 40 mmHg are only accompanied by IOP increases of 1 mmHg (reviewed by He et al [ 66 ]).…”

“…Lastly, previous authors have also demonstrated associations between body mass index (BMI) and both IOP [ 25 ] and CCT [ 26 , 27 ]. Others have shown positive relationships between blood glucose levels (BGL) and IOP [ 28 ], CCT [ 27 ] and, more equivocally, FT [ 29 ].…”