&lt;p&gt;Clinical features of pediatric idiopathic intracranial hypertension&lt;/p&gt;

Agraz, Daniel; Morgan, Linda; Jain, Samiksha; Suh, Donny W.

doi:10.2147/opth.s183087

Cited by 17 publications

(18 citation statements)

References 28 publications

(43 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 13 Agraz et al have noted a high incidence of atopy in their study cohort of children with PTC, suggesting that autoimmune component may play a role in pediatric population. 2 …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pseudotumor cerebri complicating multisystem inflammatory syndrome in a child

et al. 2021

View full text Add to dashboard Cite

Purpose: To report a case of pseudotumor cerebri (PTC) in a child associated with multisystem inflammatory syndrome in children (MIS-C), associated with presumed coronavirus disease 2019. Methods: A previously healthy 11-year-old female child presented with a 4-day history of fever, headache, vomiting, and loose stools. Laboratory investigations revealed neutrophilic leukocytosis, and markers of inflammation (C-reactive protein, ferritin, and interleukin-6) were significantly elevated. Pharyngeal swab for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by polymerase chain reaction was negative while anti-SARS-CoV-2 antibody was highly reactive. Ophthalmic evaluation for transient visual obscurations during hospital course revealed swelling of the optic disc in both eyes. Spectral-domain optical coherence tomography and ultrasonography confirmed the ophthalmoscopic findings. There was no neurologic deficit. Magnetic resonance imaging of the brain and magnetic resonance venogram revealed no structural lesion. The opening pressure of cerebrospinal fluid (CSF) was 336 mm of water, and CSF composition was normal. Results: A diagnosis of PTC associated with MIS-C was made, and the child was treated with oral acetazolamide. Edema of the optic disc regressed following therapy, and the child is under follow-up. Conclusions: PTC can occur in association with MIS-C. Clinicians need to be aware of this potential neuro-ophthalmic complication in MIS-C. Prompt diagnosis and treatment can prevent visual loss.

show abstract

“… 13 Agraz et al have noted a high incidence of atopy in their study cohort of children with PTC, suggesting that autoimmune component may play a role in pediatric population. 2 …”

Section: Discussionmentioning

confidence: 99%

“… 1 PTCS is relatively uncommon in children and is associated with variable risk factors and clinical presentation. 2 We report a case of PTCS in a child associated with multisystem inflammatory syndrome in children (MIS-C), temporally associated with coronavirus disease 2019 (COVID-19).…”

Section: Introductionmentioning

confidence: 99%

Pseudotumor cerebri complicating multisystem inflammatory syndrome in a child

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Female sexual predilection is seen among the pubertal age group of IIH [ 5 ]. Various studies have identified obesity as a risk factor for IIH in the pubertal age group [ 5 , 6 ]. By contrast, in the prepubertal age group, there is no gender predominance and obesity is not a risk factor for IIH [ 7 , 8 ].…”

Section: Discussionmentioning

confidence: 99%

Idiopathic Intracranial Hypertension in a Malaysian Preschooler

Basiron¹,

Tan²,

Ch'ng³

et al. 2021

Cureus

View full text Add to dashboard Cite

A four-year-old girl presented with a three-day history of squint and irritability. Examination showed reduced visual acuity in both eyes, the presence of a false localizing sign, and bilateral optic disc swelling. On investigation, her blood laboratory workup was within the normal range. Imaging of the brain showed no evidence of a space-occupying lesion or cerebral venous sinus thrombosis. The lumbar puncture opening pressure was 27cmH 2 0 and the cerebrospinal fluid workup was normal. The diagnosis of idiopathic intracranial hypertension (IIH) was made based on the diagnostic criteria for pseudotumor cerebri syndrome. She was successfully treated with acetazolamide with resolved symptoms and signs. This highlights the possibility of IIH presenting with inconspicuous symptoms in preschool children, which needs a high index suspicion by clinicians. Hence, solving the challenges in the workup, especially in children, is very crucial.

show abstract

“…Patients were defined as overweight if body mass index was above 25 or body weight was above the 90th percentile, and obese if body mass index was 30.0 or higher, or over the 97th percentile for age. Subsequently, we merged and combined their clinical data with the information retrieved from 15 previous clinical studies published since 2001 3,14 -32 and performed a pooled analysis. In addition to patient’s weight and gender, data that were analyzed for that purpose included the finding of papilledema and the symptoms of headache, vomiting, visual impairment, dizziness, tinnitus, and associated drug therapies regarded as precipitating factors.…”

Section: Methodsmentioning

confidence: 99%

“…12,13 The fact that pseudotumor cerebri syndrome is associated with male gender and normal body mass in children raises the possibility that the underlying mechanisms are different at a younger age. Most previous studies on pediatric pseudotumor cerebri syndrome 14 -32 included only children, which made the comparison between pediatric and adult patients challenging.…”

mentioning

confidence: 99%

Pseudotumor Cerebri Syndrome: From Childhood to Adulthood Risk Factors and Clinical Presentation

Mahajnah

Genizi²,

Zahalka

et al. 2020

J Child Neurol

View full text Add to dashboard Cite

Introduction: Although considered uncommon, pseudotumor cerebri syndrome (PTC) is a significant cause of headache among children and adults. However, the presenting symptoms may be different among diverse age groups. In the present study, we compared the risk factors and clinical presentation of PTC across life—from childhood to adulthood. Methods: A retrospective survey of PTC patients aged 7 years or older between 2011 and 2013 was carried out. Pooled analyses were performed comparing characteristics from our data with those of published data subdivided into 3 age groups: pre-young children, adolescents, and adults. Results: Our cohort consisted of 72 patients: 32 children (10 pre-young children, 22 adolescents) and 40 adults. Within the pre-young children age group: 20% were females versus 82% in the adolescent age group and 85% of the adult age group. Obesity was found in 10% of the young children group, 64% of the adolescents, and 80% of the adults. Headache was reported in 70% young children, 82% adolescents, and 83% adults. Pooled analysis of 1499 patients showed that young children with PTC tend to complain less about headache compared with older ones. Vomiting and visual impairment were most common among adolescents, and dizziness and tinnitus were most common in adults. Conclusion: PTC has different risk factors and clinical presentation throughout life. In young children, there is no gender preference and most patients are not obese. Risk factors in adolescents resemble those of adults.

show abstract

<p>Clinical features of pediatric idiopathic intracranial hypertension</p>

Cited by 17 publications

References 28 publications

Pseudotumor cerebri complicating multisystem inflammatory syndrome in a child

Pseudotumor cerebri complicating multisystem inflammatory syndrome in a child

Idiopathic Intracranial Hypertension in a Malaysian Preschooler

Pseudotumor Cerebri Syndrome: From Childhood to Adulthood Risk Factors and Clinical Presentation

Contact Info

Product

Resources

About