&lt;i&gt;Ageratum conyzoides &lt;/i&gt; L.: A review on its phytochemical and pharmacological profile

Kamboj, Anjoo; Saluja, AjayKumar

doi:10.4103/0973-8258.41171

Cited by 107 publications

(92 citation statements)

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“…Essential oils such as β-caryophyllene, δ-cadinene, epi-α-cadinol and α-cadinol have also been isolated from the A. muricata plant (Pelissler et al, 1994;Kossouoh et al, 2007). Some essential oil like beta-caryophyllene present in other plants have been reported to exhibit hypotensive and vasodilator activities (Damiani et al, 2004;Sundufu & Shoushan, 2004;Morteza-Semnani, 2006;Kamboj & Saluja, 2008) and the presence of such compounds in A. muricata might possibly contribute to the cardiovascular effects observed with the aqueous plant extract (Abdalla et al, 1995).…”

Section: Discussionmentioning

confidence: 99%

Possible mechanisms of action of the hypotensive effect ofAnnona muricata(soursop) in normotensive Sprague–Dawley rats

Nwokocha

Owu

Gordon

et al. 2012

Pharmaceutical Biology

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Section: Discussionmentioning

confidence: 99%

Possible mechanisms of action of the hypotensive effect ofAnnona muricata(soursop) in normotensive Sprague–Dawley rats

Nwokocha

Owu

Gordon

et al. 2012

Pharmaceutical Biology

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“…Many different compounds have been isolated and identified in A. conyzoides; such as kaempferol and glycoside (rhamnoside); quercetin, scutellarein, eupalestin, chromene, stigmas-7-en-3-ol, sitosterol, stigmasterol, fumaric acid, caffeic acid, saponin, pyrrolizidinic alkaloids, ageratochromene INTRODUCTION derivatives and alkane (Nyuna et al, 2010). Furthermore, Ageconyfavones A, B, and C; hexametoxyflavone; three coumarinic compounds, including 1-2 benzopirone; 1,2-desifropirrolizidinic and licopsamine have been identified in A. conyzoides (Kamboj and Saluja, 2008;Ladeira et al, 1987). The whole plant is traditionally used in management of wounds, burns and bacterial diseases (Ming, 1999).…”

Section: Introductionmentioning

confidence: 99%

“…Various pharmacological investigations have verified its antibiotic efficacy (Durodola, 1977), analgesic effect in rats (Menut et al, 1993), antioxidative effect (Jagetia et al, 2003), hepatoprotective effects (Ita et al, 2009) and as a blood booster (Ita et al, 2007). The phytochemical screening showed that A. conyzoides contains alkaloids, resins, saponins, tannins, glycosides and flavonoids (Kamboj and Saluja, 2008). Many different compounds have been isolated and identified in A. conyzoides; such as kaempferol and glycoside (rhamnoside); quercetin, scutellarein, eupalestin, chromene, stigmas-7-en-3-ol, sitosterol, stigmasterol, fumaric acid, caffeic acid, saponin, pyrrolizidinic alkaloids, ageratochromene INTRODUCTION derivatives and alkane (Nyuna et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Antioxidant and cytotoxic activities of Ageratum conyzoides stems

Nasrin

2013

Int Curr Pharm J

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Modern civilization is facing more than hundreds of disorders associated with free radicals and natural antioxidants from non-edible plants are gaining importance to fight these disorders. The intention of this report is to evaluate a well known medicinal weed Ageratum conyzoides stems for its antioxidant and cytotoxic Effects. Antioxidant potentiality of the crude methanolic extract of the Ageratum conyzoides (AC) stems was investigated on DPPH scavenging activity, reducing ability, total antioxidant capacity as well as total phenolic contents. Cytotoxic study was done by brine shrimp lethality bioassay and vincristin sulphate was used as standard. The total phenols and total antioxidant capacity of AC was found to be 38.125 ± 2.01mg/g equivalent of gallic acid and 333.37 ± 4.22mg/gm equivalent of ascorbic acid, respectively. The percentage (%) scavenging of DPPH free radical of the extract was found to be concentration dependent with IC50 value 46.01 ± 2.23µg/ml while IC50 value of standard ascorbic acid was found to be 29.56 ± 0.11?g/ml. The reducing power of AC was found to be concentration dependent. The cytotoxicity exhibited by AC was found promising with LC50 value 1.32?g/ml, comparing with the LC50 (0.689?g/ml) values of vincristin sulphate. The present investigation suggests that Ageratum conyzoides possesses remarkable antioxidant and cytotoxic property.DOI: http://dx.doi.org/10.3329/icpj.v2i2.13195 International Current Pharmaceutical Journal 2013, 2(2): 33-37

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“…It is a weed, commonly called Billygoat-weed, Goatweed etc., and generally found in cultivated fields and other ecosystems such as pastures, grasslands, wastelands and even forest areas. 8 The plant is scientifically reported to possess anti-oxidant, 8 wound healing, analgesic, anti-inflammatory, 9 anti-malarial, 10 anti-cancer, 11 anti-hyperglycaemic, 12 anti-ulcerogenic, 13 anti-microbial and insecticidal 14 properties. Flavonoids (eupalestin, kaempferol, sinensetin, quercetin etc), triterpenes and sterols (b-sitosterol, stigmasterol, brassicasterol etc), alkaloids (echinaline, lycopsamine etc), mono and sesquiterpenes (linalool, limonene, eugenol etc) and amino acids are reported as the phytochemical constituents from this plant.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of quality and efficacy of an ethnomedicinal plant Ageratum conyzoides L. in the management of pediculosis

Shailajan¹,

Wadke²,

Joshi³

et al. 2013

Journal of Young Pharmacists

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a b s t r a c tBackground: Infestation with the head louse, Pediculus humanus capitis, is one of the most common parasitic infestations of human worldwide. Traditionally, the main treatment for control of head lice is chemical control that includes wide variety of neurotoxic synthetic insecticides. The main difficulty posed in controlling the head louse infestation is increasing lice resistance to synthetic pediculicidal drugs. Plant-based drugs; especially essential oil components and standardized extracts have been suggested as an alternative source of materials for insect control. Ageratum conyzoides L. (Asteraceae) has been reported to possess antifungal and insecticidal properties. In the present research work, an attempt has been made to evaluate in vitro pediculicidal activity of A. conyzoides. Methods: A filter paper diffusion bioassay was carried out in order to determine the pediculicidal activity of different extracts of A. conyzoides. Results: The study elucidates the active plant part and suitable extract responsible for the therapeutic efficacy of this plant in the management of pediculosis. Conclusion: Findings of the present study indicate the potential of A. conyzoides extract to be included in the formulations as a pediculicidal agent.

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<i>Ageratum conyzoides </i> L.: A review on its phytochemical and pharmacological profile

Cited by 107 publications

References 0 publications

Possible mechanisms of action of the hypotensive effect ofAnnona muricata(soursop) in normotensive Sprague–Dawley rats

Possible mechanisms of action of the hypotensive effect ofAnnona muricata(soursop) in normotensive Sprague–Dawley rats

Antioxidant and cytotoxic activities of Ageratum conyzoides stems

Evaluation of quality and efficacy of an ethnomedicinal plant Ageratum conyzoides L. in the management of pediculosis

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