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“…In CD, the prevalence of sarcopenia was higher than in other autoimmune diseases. It ranged between 31.0 and 61.4% and the median was 40.2% [ 45 , 48 , 50 , 52 , 54 , 55 , 57 , 59 , 61 , 62 ]. There are two reasons why the numbers could have been overestimated.…”
Section: Epidemiology Of Sarcopenia In Autoimmune and Rheumatic DImentioning
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rupbmjkragerfmgwileyiopcupepmcmbcthiemesagefrontiersapsiucrarxivemeralduhksmucshluniversity-of-gavle
“…In CD, the prevalence of sarcopenia was higher than in other autoimmune diseases. It ranged between 31.0 and 61.4% and the median was 40.2% [ 45 , 48 , 50 , 52 , 54 , 55 , 57 , 59 , 61 , 62 ]. There are two reasons why the numbers could have been overestimated.…”
Section: Epidemiology Of Sarcopenia In Autoimmune and Rheumatic DImentioning
“…The mechanism of sarcopenia in IBD patients is believed to be associated with disease-related inflammation and nutritional problems. Muscle radiation attenuation, which is an inverse parameter of muscle fat content [ 101 ], has been associated with severe phenotypes of disease such as a history of a stricturing, penetrating complication, or previous resection surgery for CD [ 61 ]. In addition, sarcopenia has been associated with high disease activity assessed by the Mayo score in UC [ 45 ].…”
Section: Inflammatory Bowel Disease and Sarcopeniamentioning
“…In the future, it is relevant to add other disease outcome parameters, such as flares, change of disease phenotype, hospitalizations, and post‐operative complications and outcomes. These parameters are of interest because CT muscle attenuation radiation, as a parameter related to muscle fat content, has previously been reported to negatively affect duration of hospitalization and readmission rate after intestinal resection in IBD patients 11 and to be associated with a complicated disease phenotype in CD 10 . Because of the small number of patients in the present methodological study, we could not confirm the latter results.…”
Section: Discussionmentioning
“…Because of the fat‐saturated post‐contrast T1 images, it was not possible to reliably determine the visceral fat mass, which is a limitation of the present technique. In future studies with larger patient groups, it would be interesting to also measure other parameters of body composition like visceral and subcutaneous fat because these parameters are also reported to correlate with adverse outcomes and complicated disease phenotype in CD on CT 10,29 . There are several limitations of the present study.…”
Section: Discussionmentioning
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