Low versus high haemoglobin concentration threshold for blood transfusion for preventing morbidity and mortality in very low birth weight infants

Abstract

Low versus high haemoglobin concentration threshold for blood transfusion for preventing morbidity and mortality in very low birth weight infants (Review)

Peri-operative red blood cell transfusion in neonates and infants: NEonate and Children audiT of Anaesthesia pRactice IN Europe

“…However, the review lacked conclusive clarity relative to well tolerated lower Hb level transfusion thresholds as well as the benefits of maintaining a higher Hb level for the observed population. This stands in contrast to our analysis which revealed that current European RBC transfusion practice for neonates and infants is conducted at much lower Hb levels than recommended by the above-mentioned Cochrane review 23 …”

Peri-operative red blood cell transfusion in neonates and infants: NEonate and Children audiT of Anaesthesia pRactice IN Europe

“…However, the review lacked conclusive clarity relative to well tolerated lower Hb level transfusion thresholds as well as the benefits of maintaining a higher Hb level for the observed population. This stands in contrast to our analysis which revealed that current European RBC transfusion practice for neonates and infants is conducted at much lower Hb levels than recommended by the above-mentioned Cochrane review 23 …”

Association of hemoglobin and spontaneous closure of the ductus arteriosus during the transitional period in very low birth weight infants

“…It is important to recognize, however, that both hemoglobin and platelets contribute to blood viscosity which also influences transduc-tal flow and vessel wall perfusion. In contrast to previous studies of delayed cord clamping [19] and liberal transfusion [20] policies we demonstrated an association between hemoglobin and sDAC. This difference may be partially explained by the fact that we focused on the transitional period of life and the relationship between HB and sDAC as a primary objective.…”

Red Blood Cell Transfusions at 21 Days of Age or Older in Previously Transfusion-Naive Very Preterm Infants: Association with Neonatal Outcomes

“…Will transfusing a preterm infant after the first few weeks following birth affect any significant neonatal outcomes or impact mortality? Our study findings support the previous findings from randomized controlled trials 19 and several retrospective studies that RBC transfusion in infants is not associated with severe ROP or mortality. [20][21][22] In our cohort, infants who received transfusion after 21 days of age were more likely to have received surfactant and have a longer period of prior mechanical ventilation.…”

Peri-operative red blood cell transfusion in neonates and infants: NEonate and Children audiT of Anaesthesia pRactice IN Europe

“…However, the review lacked conclusive clarity relative to well tolerated lower Hb level transfusion thresholds as well as the benefits of maintaining a higher Hb level for the observed population. This stands in contrast to our analysis which revealed that current European RBC transfusion practice for neonates and infants is conducted at much lower Hb levels than recommended by the above-mentioned Cochrane review 23 …”

Association of hemoglobin and spontaneous closure of the ductus arteriosus during the transitional period in very low birth weight infants

“…It is important to recognize, however, that both hemoglobin and platelets contribute to blood viscosity which also influences transduc-tal flow and vessel wall perfusion. In contrast to previous studies of delayed cord clamping [19] and liberal transfusion [20] policies we demonstrated an association between hemoglobin and sDAC. This difference may be partially explained by the fact that we focused on the transitional period of life and the relationship between HB and sDAC as a primary objective.…”

Red Blood Cell Transfusions at 21 Days of Age or Older in Previously Transfusion-Naive Very Preterm Infants: Association with Neonatal Outcomes

“…Will transfusing a preterm infant after the first few weeks following birth affect any significant neonatal outcomes or impact mortality? Our study findings support the previous findings from randomized controlled trials 19 and several retrospective studies that RBC transfusion in infants is not associated with severe ROP or mortality. [20][21][22] In our cohort, infants who received transfusion after 21 days of age were more likely to have received surfactant and have a longer period of prior mechanical ventilation.…”

Peri-operative red blood cell transfusion in neonates and infants: NEonate and Children audiT of Anaesthesia pRactice IN Europe

“…However, the review lacked conclusive clarity relative to well tolerated lower Hb level transfusion thresholds as well as the benefits of maintaining a higher Hb level for the observed population. This stands in contrast to our analysis which revealed that current European RBC transfusion practice for neonates and infants is conducted at much lower Hb levels than recommended by the above-mentioned Cochrane review 23 …”

Association of hemoglobin and spontaneous closure of the ductus arteriosus during the transitional period in very low birth weight infants

“…It is important to recognize, however, that both hemoglobin and platelets contribute to blood viscosity which also influences transduc-tal flow and vessel wall perfusion. In contrast to previous studies of delayed cord clamping [19] and liberal transfusion [20] policies we demonstrated an association between hemoglobin and sDAC. This difference may be partially explained by the fact that we focused on the transitional period of life and the relationship between HB and sDAC as a primary objective.…”

Red Blood Cell Transfusions at 21 Days of Age or Older in Previously Transfusion-Naive Very Preterm Infants: Association with Neonatal Outcomes

“…Will transfusing a preterm infant after the first few weeks following birth affect any significant neonatal outcomes or impact mortality? Our study findings support the previous findings from randomized controlled trials 19 and several retrospective studies that RBC transfusion in infants is not associated with severe ROP or mortality. [20][21][22] In our cohort, infants who received transfusion after 21 days of age were more likely to have received surfactant and have a longer period of prior mechanical ventilation.…”