Loop diathermy excision of the cervical transformation zone in patients with abnormal cervical smears

Management of female prisoners with abnormal cervical cytology

“…Our results suggest that if a see and treat policy were introduced the overtreatment rate would be similar to that in other see and treat studies,3 but most women would be cured of their condition at first presentation. In this group of women, however, the advantages of prompt successful treatment outweigh possible overtreatment because of the high incidence of high grade disease and the high default rate from treatment and follow up.…”

Controversies in Management: Management of women with mild dyskaryosis Cytological surveillance avoids overtreatment

“…This has been made possible by the widespread introduction of large loop excision of the transformation zone. In one of the largest reported series looking at the procedure 27% of the women treated had no abnormality or koilocytic atypia 12. If we include those women with grade I cervical intraepithelial neoplasia, which has a low risk of progression to invasive disease, the overtreatment rate rises to 45%.…”

Large loop excision of the transformation zone: A histological audit

“…Such morbidity can be justified if the diagnosis of cervical neoplasia is confirmed, given that the primary purpose of treatment is the prevention of invasive cancer. In an early study of 616 patients a negative histology rate of 27 per cent was recorded (Luesley et al, 1990). In a retrospective audit of 913 patients, an 18 per cent negative histology rate was reported (Stratton et al, 1994).…”

“…LLETZ combines the advantages of ablative treatment with the benefit of detailed histological assessment. LLETZ also has expanded the opportunities for seeing and treating patients at their first visit to the clinic, thus improving the efficiency of colposcopy services (Bigrigg et al, 1990;Luesley et al, 1990). Any treatment of the transformation zone is associated with morbidity.…”