Longitudinal Relationship between Plasma Reactive Oxygen Metabolites and Periodontal Condition in the Maintenance Phase of Periodontal Treatment

Machida, Tatsuya; Tomofuji, Takaaki; Ekuni, Daisuke; Yamane, Mayu; Yoneda, Toshiki; Kawabata, Yuya; Kataoka, Koichi; Tamaki, Naofumi; Morita, Manabu

doi:10.1155/2014/489292

Cited by 11 publications

(10 citation statements)

References 41 publications

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“…Overwhelming evidence indicates that oxidative stress plays a central role in the periodontal tissue and alveolar bone destruction [ 17 , 18 ]. Indeed, a recent clinical study indicated that an increase in plasma reactive oxygen metabolites (ROM) levels was associated with that in the clinical attachment level in periodontal patients whose plasma ROM level was low [ 19 ].…”

Section: Increase In Oxidative Stress and Lipid Oxidation Caused Bmentioning

confidence: 99%

Periodontal Disease-Induced Atherosclerosis and Oxidative Stress

et al. 2015

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Periodontal disease is a highly prevalent disorder affecting up to 80% of the global population. Recent epidemiological studies have shown an association between periodontal disease and cardiovascular disease, as oxidative stress plays an important role in chronic inflammatory diseases such as periodontal disease and cardiovascular disease. In this review, we focus on the mechanisms by which periodontopathic bacteria cause chronic inflammation through the enhancement of oxidative stress and accelerate cardiovascular disease. Furthermore, we comment on the antioxidative activity of catechin in atherosclerosis accelerated by periodontitis.

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Section: Increase In Oxidative Stress and Lipid Oxidation Caused Bmentioning

confidence: 99%

Periodontal Disease-Induced Atherosclerosis and Oxidative Stress

et al. 2015

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“…They observed a positive correlation between baseline plasma RM levels and mean an alteration in LCA with mean alteration in the RM levels and bleeding on probing. 21 Significant results were also observed while making an intragroup comparison in relation of meaning GCF resistin levels in both the study groups at different time intervals. In inflammatory conditions such as periodontal infection, expression of resistin by inflammatory cells might be responsible for an increase in increase in resistin levels in patients with chronic periodontitis.…”

Section: Discussionmentioning

confidence: 85%

Resistin and Plasma-reactive Oxygen Metabolite Levels in Obese and Nonobese Individuals with Chronic Periodontitis in Response to Nonsurgical Periodontal Therapy

Varghese

Prashant

Dodani

et al. 2018

The Journal of Contemporary Dental Practice

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Aim: To assess and compare the impact of non-surgical periodontal therapy on plasma reactive oxygen metabolites and resistin values in chronic periodontitis obese and non-obese patients. Materials and methods: Total 200 subjects were included in the present study and were broadly divided into two study groups with 100 patients in each group as follows: group A: Obese patients with chronic periodontitis, group B: Non-obese, normal weight patients with chronic periodontitis. Various following periodontal parameter were calculated at the baseline time and two months after the nonsurgical periodontal therapy. Plasma reactive oxygen metabolite (RM) and serum and GCF resistin levelswere evaluated. Assessment of all the results was done by Statistical Package for Social Sciences (SPSS) software. Results: Significant results were obtained while doing an intergroup comparison of clinical attachment levels between two study groups. Significant results were obtained while comparing the clinical attachment levels in both the study groups at different time intervals. Significantmki 9 reduction in the RM was seen in Group B subjects in comparison to Group A subjects 2 months after nonsurgical periodontal therapy. Conclusion: In patients with chronic periodontitis, obesity can be considered as an important factor in the alteration of resistin levels. Clinical significance: Obese patients should be motivated for reducing weight so that periodontal therapy and other treatment modalities could be carried out more effectively.

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“…37 Previous study also reported the connection between clinical attachment level with the escalation of reactive oxygen metabolites (ROM). 38 Moreover, mitochondria as the major producer of ROS in cells causes a chronic over production which leads to increased oxidation of LDL in atherosclerosis development. 39 Another study reported that Porphyromonas gingivalis infection might increase the LDL levels and induces hypercholesterolemia.…”

Section: Discussionmentioning

confidence: 99%

The Association between Periodontal Conditions and Serum Lipids among Elderly Participants in Gadjah Mada Medical Centre, Yogyakarta

Widita¹,

Hanindriyo²,

Widyaningrum³

et al. 2017

J Dent Indones

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Prevention of cardiovascular diseases by controlling risk factors at an early stage is very important. Objective: To determine the relationship between periodontal conditions with serum lipids among the elderly. Methods: Total of 78 participants (56 males and 32 females) who were in the age range of 60-76 years were selected for the current study. A logistic regression analysis was used to evaluate the association between periodontal conditions and serum lipid profile. Periodontal conditions was recorded as the maximum score of pocket depth (PD) and loss of attachment (LoA) score which presented in the participants, while levels of total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), and triglycerides (TG) were measured for the serum lipids profile. Age, gender, BMI, high blood pressure, pattern of dental visit, hypertension and cholesterol medication, number of teeth, PD, and LoA were included in the model as independent variable. TC, HDL, LDL, and TG were used as dependent variables. Results: According to the results of the logistic regression analysis, loss of attachment >6 mm was associated with TC (p<0.01;, while PD had no association with serum lipids (p>0.05). Conclusion: This study indicates that subjects with greater loss of attachment significantly associated with higher levels of serum TC and LDL. This may suggest that elderly people with greater loss of attachment are potentially at risk of having serum lipid impairment.

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Longitudinal Relationship between Plasma Reactive Oxygen Metabolites and Periodontal Condition in the Maintenance Phase of Periodontal Treatment

Cited by 11 publications

References 41 publications

Periodontal Disease-Induced Atherosclerosis and Oxidative Stress

Periodontal Disease-Induced Atherosclerosis and Oxidative Stress

Resistin and Plasma-reactive Oxygen Metabolite Levels in Obese and Nonobese Individuals with Chronic Periodontitis in Response to Nonsurgical Periodontal Therapy

The Association between Periodontal Conditions and Serum Lipids among Elderly Participants in Gadjah Mada Medical Centre, Yogyakarta

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