Long‐term results in low‐fluence 1064‐nm Q‐Switched Nd:<scp>YAG</scp> laser for melasma: Is it effective?

Gökalp, Hilal; Akkaya, Ayşe Deniz; Oram, Yasemin

doi:10.1111/jocd.12253

Cited by 40 publications

(46 citation statements)

References 36 publications

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“…However, some authors asserted that low‐fluence QSNY has only a temporary effect on melasma and that the recurrence rate is high on long‐term follow‐up. In addition, complications such as rebound hyperpigmentation and mottled hypopigmentation have been reported with various frequencies . Mottled hypopigmentation is of serious concern as it rarely recovers spontaneously .…”

Section: Introductionmentioning

confidence: 99%

Low‐fluence Q‐switched Nd:YAG laser for the treatment of melasma in Asian patients

Choi

Lee

Seo

et al. 2018

J of Cosmetic Dermatology

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Background: Melasma is a common acquired facial pigmentary disorder that is resistant to various modalities of treatment. Recently, the low-fluence 1064-nm Qswitched neodymium-doped yttrium aluminum garnet laser (QSNY) has emerged as the new gold standard of melasma treatment in Asia. Objective: To evaluate the efficacy and safety of low-fluence 1064-nm QSNY in Asian patients with melasma. Methods: Data of patients with melasma treated with low-fluence QSNY in the department of dermatology at the Korea University Anam Hospital were reviewed retrospectively. A 1064-nm QSNY with 8 mm spot size and fluence of 1.2-2.0 J/cm 2 at 10 Hz was used. The results were evaluated using the modified Melasma Area and Severity Index (mMASI) score and the physician's global assessment (PGA).Results: A total of 40 Korean patients with Fitzpatrick skin type III to IV were included. Patients were treated for a median of 10 sessions at a median of 1-week intervals. The mean mMASI score decreased by 54.23% from a baseline of 3.19 ± 2.64 to 1.46 ± 1.06 after treatment. On PGA, 1 out of 40 patients (2.5%) showed excellent improvement, 14 (35%) good, 15 (37.5%) fair, 6 (15%) poor, and 4 (10%) no improvement. However, two patients showed mottled hypopigmentation and rebound hyperpigmentation. Conclusion:Low-fluence 1064-nm QSNY appears to be a safe and effective treatment for Asian patients with melasma.

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Section: Introductionmentioning

confidence: 99%

Low‐fluence Q‐switched Nd:YAG laser for the treatment of melasma in Asian patients

Choi

Lee

Seo

et al. 2018

J of Cosmetic Dermatology

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“…The other is a 1064 nm Q‐switched neodymium‐doped:yttrium aluminum garnet (Nd:YAG) laser recognizes as effective and safe treatment for moderate to severe melasma patients with dermal and mixed type melasma. There is, however, a high likelihood of recurrence when the long‐term results are considered, and side effects have been seen particularly in Asian patients such as PIH and mottled hypopigmentation. Recently, the picosecond domain laser has been introduced for various pigmentary disorders such as melasma.…”

Section: Introductionmentioning

confidence: 99%

Efficacy and safety of a novel picosecond laser using combination of 1 064 and 595 nm on patients with melasma: A prospective, randomized, multicenter, split‐face, 2% hydroquinone cream‐controlled clinical trial

et al. 2017

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A 750 picosecond laser using 1 064 and 595 nm was effective and safe for the treatment of Korean melasma patients. The picosecond laser with dual-wavelength used in this study can reduce the photothermal effect generated during the removal of pigment and total duration of the procedure, and can be expected to reduce the occurrence of adverse events. Lasers Surg. Med. 49:899-907, 2017. © 2017 Wiley Periodicals, Inc.

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“…Although the laser treatment was discontinued, all of the patients exhibited some degree of rebound hyperpigmentation [19] . Gokalp and co-workers found the melasma recurrence rates from low-fluence 1064-nm QS laser was high after one-year follow-up (60% of whom had responded well to the initial treatment) [2] . Melasma can be safely and successfully treated with sub-thermolytic 1064-nm QSNY therapy if correctly applied, and even low fluences (1.6 J/cm 2 ) can be effective to prevent complications.…”

Section: Q-switched Lasersmentioning

confidence: 99%

“…For the second-line therapy, there are applications of chemical peeling agents. The third-line therapy is the use of technology, including laser modalities and intense pulsed light (IPL) [2,9] . The major disadvantages of topical agents are the need for long-term utilization and the gradual or limited treatment responses.…”

Section: Melasma and Energy-based Devicesmentioning

confidence: 99%

“…There are three classified clinical patterns: centrofacial (most common), malar, and mandibular. According to Wood's light examination and histology, melasma can be epidermal, dermal, and mixed [1][2][3] . Despite the fact that melasma pathogenesis is not well understood, the most universally accepted cause is a hyperactivity of melanocytes when stimulated by UV light exposure.…”

Section: Melasma and Energy-based Devicesmentioning

confidence: 99%

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Energy-based devices for treatment of melasma

Jordão

Rebellato

2017

J Surg Dermatol

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Melasma, as a pigmentation disorder, induces significant stress to the patients and its recurrent nature remains a challenge in clinical practice. Treatment is based on a variety of mechanisms to prevent and/or stop the pigment production process by destroying the deposited pigment for removal or release, by peeling cells to improve their turnover, and by reducing inflammation. The use of appropriate devices and correct settings are crucial in the treatment of melasma. Cases unresponsive to topical bleaches or chemical peels should be referred for laser therapy. It is important that a maintenance therapy to avoid the recurrence of melasma be indicated. In this paper, we review energy-based devices for melasma treatment.

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Long‐term results in low‐fluence 1064‐nm Q‐Switched Nd:YAG laser for melasma: Is it effective?

Abstract: The recurrence of low-fluence 1064-nm QS-Nd:YAG laser rates in melasma was high when the long-term results were considered. This result may be attributed to certain patient and treatment-related factors.

Cited by 40 publications

References 36 publications

Low‐fluence Q‐switched Nd:YAG laser for the treatment of melasma in Asian patients

Low‐fluence Q‐switched Nd:YAG laser for the treatment of melasma in Asian patients

Efficacy and safety of a novel picosecond laser using combination of 1 064 and 595 nm on patients with melasma: A prospective, randomized, multicenter, split‐face, 2% hydroquinone cream‐controlled clinical trial

Energy-based devices for treatment of melasma

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