Long-term in vivo performances of polylactide/iron oxide nanoparticles core–shell fibrous nanocomposites as MRI-visible magneto-scaffolds

Abstract

There is a growing interest in magnetic nanocomposites in biomaterials science. In particular, nanocomposites that combine poly(lactide) (PLA) nanofibers and super paramagnetic iron oxide nanoparticles (SPIONs), which can be obtained...

Iron oxide – poly(m-anthranilic acid)–poly(ε-caprolactone) electrospun composite nanofibers: fabrication and properties

“…Homogeneous Fe 2 O 3 /P3ANA/PCL electrospun composite nanofiber meshes can potentially be used as skin patches due to the growing interest in magnetic nanocomposites in biomaterials science. 46 The current study shows that the inclusion of Fe 2 O 3 and P3ANA allows tuning the morphology and the electrical conductivity, which promises the use of such composite nanofibers in nerve systems.…”

Recent trends in preparation and biomedical applications of iron oxide nanoparticles

“…Poly (lactide)@SPIONs nanofibers were prepared and implanted in rats via peritoneal cavity for 6 months. Long-term MRI and histological analyses revealed that the degradation of this SPIONs nanofibers was quite slowly, as evidence that they were easily detected after 6 months post-implantation [ 62 ]. Bi-layer, which was consisted of oleic acid and methoxy-polyethylene glycol-phospholipid was coated in SPIONs, was named as SPION-PEG2000.…”