Intern. Med. volume 35, issue 10, P772-778 1996 DOI: 10.2169/internalmedicine.35.772 View full text
Shinji TERAMOTO, Takeshi MATSUSE, Eiichi SUDO, Eijiro OHGA, Hirofumi KATAYAMA, Masashi SUZUKI, Yasuyoshi OUCHI, Yoshinosuke FUKUCHI

Abstract: To investigate the long-term effects of the inhaled anticholinergic bronchodilator, oxitropium bromide (OTB), on lung function, exercise capacity, and dyspnea in patients with chronic obstructive pulmonary disease (COPD), spirometry and symptom-limited exercise testing before and 1, 6, and 12 months after the regular use of OTB (600 |ig/day) were performed in 12 patients with the use of OTB(mean age 69.9+3.1 years; FEVx/FVC53.3+1.6%) as well as in 12 control patients who were not treated with OTB(Mean age 68.…

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