Long-term control of choroidal neovascularization in quiescent congenital toxoplasma retinochoroiditis with photodynamic therapy: 4-year results

Abstract

Photodynamic therapy seems to be a safe and effective approach to the long-term control of subfoveal CNV associated with toxoplasmic retinochoroiditis. Further trials are needed to validate these findings.

Modulated Gene Expression of Toxoplasma gondii Infected Retinal Pigment Epithelial Cell Line (ARPE-19) via PI3K/Akt or mTOR Signal Pathway

“…Choroidal neovascularization is a severe complication of ocular toxoplasmic retinochoroiditis [ 16 ]. Increased expression of VEGF, in addition to compromise in Bruch’s membrane and inflammation secondary to infection with T. gondii , may contribute to neovascular disease in ocular toxoplasmosis [ 29 ].…”

Modulated Gene Expression of Toxoplasma gondii Infected Retinal Pigment Epithelial Cell Line (ARPE-19) via PI3K/Akt or mTOR Signal Pathway

“…Choroidal neovascularization is a severe complication of ocular toxoplasmic retinochoroiditis [ 16 ]. Increased expression of VEGF, in addition to compromise in Bruch’s membrane and inflammation secondary to infection with T. gondii , may contribute to neovascular disease in ocular toxoplasmosis [ 29 ].…”

Intravitreal aflibercept for choroidal neovascularization associated with chorioretinitis: a pilot study

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Successful Treatment of Toxoplasmosis-Associated Choroidal Neovascular Lesions With Bevacizumab and Antiparasitic Therapy

“…Photodynamic therapy appears to be effective but with higher costs. 8 Benevento et al 2 used intravitreal 0.5-mg ranibizumab (Lucentis; Genentech, Inc) under concurrent systemic administration of oral pyrimethamine, sulfadiazine, and leucovorin. Ranibizumab may be given once a month and can be continued for at least one to two treatments beyond resolution of CNV.…”

Modulated Gene Expression of Toxoplasma gondii Infected Retinal Pigment Epithelial Cell Line (ARPE-19) via PI3K/Akt or mTOR Signal Pathway

“…Choroidal neovascularization is a severe complication of ocular toxoplasmic retinochoroiditis [ 16 ]. Increased expression of VEGF, in addition to compromise in Bruch’s membrane and inflammation secondary to infection with T. gondii , may contribute to neovascular disease in ocular toxoplasmosis [ 29 ].…”

Intravitreal aflibercept for choroidal neovascularization associated with chorioretinitis: a pilot study

“……”

Successful Treatment of Toxoplasmosis-Associated Choroidal Neovascular Lesions With Bevacizumab and Antiparasitic Therapy

“…Photodynamic therapy appears to be effective but with higher costs. 8 Benevento et al 2 used intravitreal 0.5-mg ranibizumab (Lucentis; Genentech, Inc) under concurrent systemic administration of oral pyrimethamine, sulfadiazine, and leucovorin. Ranibizumab may be given once a month and can be continued for at least one to two treatments beyond resolution of CNV.…”

Modulated Gene Expression of Toxoplasma gondii Infected Retinal Pigment Epithelial Cell Line (ARPE-19) via PI3K/Akt or mTOR Signal Pathway

“…Choroidal neovascularization is a severe complication of ocular toxoplasmic retinochoroiditis [ 16 ]. Increased expression of VEGF, in addition to compromise in Bruch’s membrane and inflammation secondary to infection with T. gondii , may contribute to neovascular disease in ocular toxoplasmosis [ 29 ].…”

Intravitreal aflibercept for choroidal neovascularization associated with chorioretinitis: a pilot study

“……”

Successful Treatment of Toxoplasmosis-Associated Choroidal Neovascular Lesions With Bevacizumab and Antiparasitic Therapy

“…Photodynamic therapy appears to be effective but with higher costs. 8 Benevento et al 2 used intravitreal 0.5-mg ranibizumab (Lucentis; Genentech, Inc) under concurrent systemic administration of oral pyrimethamine, sulfadiazine, and leucovorin. Ranibizumab may be given once a month and can be continued for at least one to two treatments beyond resolution of CNV.…”