Long term clinical course of Tourette syndrome

Rizzo, Renata; Gulisano, Mariangela; Calì, Paola V.; Curatolo, Paolo

doi:10.1016/j.braindev.2011.11.006

Cited by 83 publications

(86 citation statements)

References 29 publications

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“…The reviewed studies were conducted in several countries, including the US (n = 26) [24, 32-33, 37, 43, 45-47, 51, 53, 59-60, 63-64, 67-68, 72-74, 76-78, 86-87, 89, 91]; Germany (n = 6) [40,44,48,54,79,92]; Switzerland (n = 3) [23, 82,84]; the Netherlands (n = 4) [13,38,52,66]; Australia (n = 3) [14,[49][50]; Turkey (n = 3) [41,61,80]; Brazil (n = 2) [39,83]; Spain (n = 2) [36,85]; Italy (n = 2) [70,71]; Taiwan (n = 2) [55][56]; Iran (n = 1) [42]; UK (n = 1) [69]; Norway (n = 1) [35]; Hungary (n = 1) [88]; France (n = 1) [58]; Canada (n = 1) [18]; Japan (n = 1) [81]; Greece (n = 1) [90]; and Mexico (n = 1) [57]. Four studies were conducted in two or more countries [34,62,65,75].…”

Section: Description Of Studiesmentioning

confidence: 99%

“…As shown in Table 2, studies examining the QL of children with the following diagnoses of mental disorder were included: attention deficit hyperactivity disorder (ADHD; n = 27) [18; 32-57]; autism spectrum disorder (n = 10) [58][59][60][61][62][63][64][65][66][67]; Gilles de la Tourette syndrome or other tic disorder (n = 6) [68][69][70][71][72][73]; bipolar spectrum disorders (n = 5) [74][75][76][77][78]; enuresis (n = 3) [79][80][81]; separation anxiety disorder and anxiety disorders (n = 3) [82][83][84]; eating disorders (n = 2) [85][86]; major depressive disorder (n = 2) [87][88]; conduct disorder (n = 1) [89]; obsessive-compulsive disorder (n = 1) [24]; and learning disabilities (n = 1) [90]. Five studies included diverse diagnoses of a mental disorder [13-14, 23, 91-92].…”

Section: Description Of Studiesmentioning

confidence: 99%

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Applying a developmental approach to quality of life assessment in children and adolescents with psychological disorders: challenges and guidelines

Carona

Silva

Moreira

2014

Expert Review of Pharmacoeconomics & Outcomes Research

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Research on the quality of life (QL) of children/adolescents with psychological disorders has flourished over the last few decades. Given the developmental challenges of QL measurements in pediatric populations, the aim of this study was to ascertain the extent to which a developmental approach to QL assessment has been applied to pedopsychiatric QL research. A systematic literature search was conducted in three electronic databases (PubMed, PsycINFO,SocINDEX) from 1994 to May 2014. Quantitative studies were included if they assessed the self or proxy-reported QL of children/adolescents with a psychological disorder. Data were extracted for study design, participants, QL instruments and informants, and statistical approach to age-related specificities. The systematic review revealed widespread utilization of developmentally appropriate QL instruments but less frequent use of both self and proxy reports and an inconsistent approach to age group specificities.Methodological guidelines are discussed to improve the developmental validity of QL research for children/adolescents with mental disorders.

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Section: Description Of Studiesmentioning

confidence: 99%

Section: Description Of Studiesmentioning

confidence: 99%

Applying a developmental approach to quality of life assessment in children and adolescents with psychological disorders: challenges and guidelines

Carona

Silva

Moreira

2014

Expert Review of Pharmacoeconomics & Outcomes Research

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“…38,39 Of note, GTS patients with comorbidities have less satisfactory symptom control with pharmacologic treatment compared with pure GTS patients. 37 …”

Section: The Spectrum Of Gilles De La Tourette Syndrome Throughout Dementioning

confidence: 97%

“…37 However, it is important to point out that in most cases tics will largely remit. 38,39 Of note, GTS patients with comorbidities have less satisfactory symptom control with pharmacologic treatment compared with pure GTS patients.…”

Section: The Spectrum Of Gilles De La Tourette Syndrome Throughout Dementioning

confidence: 99%

Tics and Tourette Syndrome

2015

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“…In another controlled study, individuals with GTS had poorer psychosocial outcomes than healthy controls and this was associated not only with tic severity but also specifically ADHD and OCD 127 . Other factors encountered in patients with GTS but for which the ADHD is largely responsible, include maladaptive behaviours and decreased cognitive functioning in young people 124 , greater substance abuse, more aggression and more encounters with the justice system 128 . In summary, there is a consensus that comorbidities in general have a profound negative effect on the QoL, social functioning and peer relationships of patients with GTS while people with GTS and ADHD have significantly more maladaptive behaviours across the lifespan.…”

Section: Shared Genetic Basis With Other Neuropsychiatric and Neurolomentioning

confidence: 99%

Gilles de la Tourette Syndrome

Stern¹,

Robertson²

2012

Current Themes in Psychiatry in Theory and Practice

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The unstructured abstract of 200 words maximum should summarize the main points of the article. All information mentioned in the abstract must be addressed somewhere in the main article. The abstract should not contain references or display item citations. Gilles de la Tourette Syndrome (GTS), a reasonably common disorder, has had a long, tortuous and somewhat controversial history. First and well described in the 18th century 1,2 , the main features of GTS have, however, remained fairly constant. The core diagnostic features are multiple motor and one or more vocal (phonic) tics lasting for over a year. In addition, almost pathognomic, but not necessary, features described in the early documentations include coprolalia (involuntary, inappropriate swearing), and echophenomena (copying behaviours), as well as many co-morbidities and psychopathologies 3 . Introduction [suggested 500 words, is 544 words -8 refs] Mary Robertson Thoughts for Mary -Your word count when combining sections 1 and 2 is 1001 (1000 limit)-so OKGTS was originally described in France and the majority of early literature came from and standardised schedules such as diagnostic confidence, measurement of severity, QoL, and assessment of both co-morbidities and co-existent psychopathologies are currently available.Large international collaborative consortia are engaged in studies exploring aetiological factors in particular, and some international treatment studies are also underway. Perhaps as a result of earlier small patient numbers, the treatment trials have given good clues to management, but unsurprisingly systematic reviews and meta-analyses have been hampered, giving disappointing, if not unexpected, results. Intriguingly medications from the typical NRDP -Gilles de la Tourette Syndrome 3 antipsychotic family including haloperidol, which first had documented success in 1961 6,7 are still being used, although successive generations of "atypicals" are currently more in vogue,as are medications such as alpha-2-adrenergic agonists. Interestingly, haloperidol remains the only medication prescribed on licence in many parts of the world. In contrast to disorders such as ADHD, in which it is clear which treatments work and which do not require further study 8 , a variety of treatment studies in GTS are still being undertaken, including using other medications (trying to improve efficacy and reduce side effects), behavioural therapies, deep brain stimulation (for refractory cases), and other more "alternative" methods such as "orthotics" (teeth braces). The GTS community has to first agree on how common GTS is and then seek funding for research in the areas of major importance.2. Epidemiology [suggested 500 words, is 444 words, 6 additional refs] Mary Robertson GTS was for many years thought to be not only very rare, but a bizarre curiosity, with sporadic case reports peppering the literature. The belief that GTS was uncommon at the very least was held by many until Comings 9 controversially suggested that GTS occurred in between 0.66% and...

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Long term clinical course of Tourette syndrome

Cited by 83 publications

References 29 publications

Applying a developmental approach to quality of life assessment in children and adolescents with psychological disorders: challenges and guidelines

Applying a developmental approach to quality of life assessment in children and adolescents with psychological disorders: challenges and guidelines

Tics and Tourette Syndrome

Gilles de la Tourette Syndrome

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