Long-term Chinese herbs decoction administration for management of hot flashes associated with endocrine therapy in breast cancer patients

Dong, Xue; Sun, Hong; Li, Pingping

doi:10.1007/s11670-011-0074-7

Cited by 10 publications

(11 citation statements)

References 37 publications

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“…Specifically, guarana and Ganoderma lucidum may be beneficial in treating fatigue amongst breast cancer patients (40,45) whereas QOL may be improved by use of Ganoderma lucidum, essiac, and Chinese medicinal herbal mixtures including YZDS and THL-P (33,34,38,40). Another Chinese medicinal herbal mixture, Shu-gan-liang-xue may also be beneficial in alleviating menopausal symptoms (35). There is also some evidence to suggest glutamine supplementation may be beneficial in the treatment of oral mucositis in breast cancer patients.…”

Section: Discussionmentioning

confidence: 99%

“…Zhuang et al (2012) found no significant improvement in treatment toxicity symptoms between RG-CMH and placebo group (P > 0.05) (36). Two studies were of neutral quality (33,36), whereas the other 2 were rated negative quality (34,35).…”

Section: Chinese Herbal Medicine Mixturesmentioning

confidence: 95%

“…Similarly, found physical and emotional QOL significantly increased by six and 13 points, respectively (P < 0.001; P D 0.008) (33,34). Hot flashes significantly improved in women receiving shu-gan-liang-xue mixture compared to usual care with 4% more women in the shu-gan-liang-xue group reporting their symptoms had disappeared, and 22.3% more women reporting their symptoms were alleviated compared to placebo (P D 0.013) (35). Zhuang et al (2012) found no significant improvement in treatment toxicity symptoms between RG-CMH and placebo group (P > 0.05) (36).…”

Section: Chinese Herbal Medicine Mixturesmentioning

confidence: 97%

“…Four studies, including 2 RCT, 1 nonrandomized experimental study and 1 pre-post study examined Chinese medicinal herbal mixtures and QOL, therapy-toxicity symptoms and hot flashes (33)(34)(35)(36). Sample sizes ranged from 44 to 82 in which a variety of herbal mixtures were trialed for 6 wk to 2 yr (33)(34)(35)(36).…”

Section: Chinese Herbal Medicine Mixturesmentioning

confidence: 99%

“…Sample sizes ranged from 44 to 82 in which a variety of herbal mixtures were trialed for 6 wk to 2 yr (33)(34)(35)(36). Two studies found significant improvements in QOL with Tien Hsien Liquid Practical (THL-P) and Yun Zhi Dan Shen (YZDS) (33,34).…”

Section: Chinese Herbal Medicine Mixturesmentioning

confidence: 99%

See 4 more Smart Citations

The Impact of Complementary and Alternative Medicines on Cancer Symptoms, Treatment Side Effects, Quality of Life, and Survival in Women With Breast Cancer—A Systematic Review

Leggett

Koczwara

Miller

2015

Nutrition and Cancer

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Breast cancer is the most common form of cancer amongst women. Women with breast cancer frequently consult dietitians for advice, and increasingly advice on complementary alternative medicines (CAM). The aim of this systematic review was to evaluate evidence of CAM administered orally on cancer-related outcomes. Databases were searched for studies recruiting women with a history of breast cancer reporting on the use of CAM administered orally as tablets, capsules, powders, and liquids for any 1 or more of the following: alleviation of cancer-related symptoms and treatment side effects, improvement to quality of life, physical and emotional wellbeing, survival, and mortality. Twenty-two studies were identified as meeting the inclusion criteria. Ten CAM categories were established with no more than 4 articles published in each category. Although the evidence is of varying quality there is some data to support that guarana and Ganoderma lucidum may improve fatigue, whereas glutamine may also be effective in improving oral mucositis symptoms. Overall, the current available evidence is inconclusive to make definitive recommendations regarding the effectiveness for individuals' use of CAM in women with breast cancer. Further high-quality randomized controlled trials exploring safety, toxicity, and other potential adverse effects of CAM are required.

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Section: Discussionmentioning

confidence: 99%

Section: Chinese Herbal Medicine Mixturesmentioning

confidence: 95%

Section: Chinese Herbal Medicine Mixturesmentioning

confidence: 97%

Section: Chinese Herbal Medicine Mixturesmentioning

confidence: 99%

Section: Chinese Herbal Medicine Mixturesmentioning

confidence: 99%

See 3 more Smart Citations

The Impact of Complementary and Alternative Medicines on Cancer Symptoms, Treatment Side Effects, Quality of Life, and Survival in Women With Breast Cancer—A Systematic Review

Leggett

Koczwara

Miller

2015

Nutrition and Cancer

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Acupuncture as an adjuvant therapy for management of treatment-related symptoms in breast cancer patients

Jang

Ko²,

Sasaki³

et al. 2020

Medicine

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Background: Although randomized controlled trials have revealed the considerable effectiveness of acupuncture in breast cancer patients, there have been no studies exploring current acupuncture research trends for treatment induced various symptoms in breast cancer patients. This review evaluated the effectiveness of acupuncture for treatment-induced symptoms in breast cancer patients. Methods: We performed a systematic review and meta-analysis of the literature regarding acupuncture to treat symptoms associated with breast cancer therapies. The following databases were searched for relevant RCTs published before June 2018: MEDLINE, EMBASE, the Cochrane Library, AMED, CINAHL, OASIS, CNKI, and CiNii. Results: Among the 19,483 records identified, 835 articles remained after screening titles and abstracts. A total of 19 RCTs were included in this qualitative synthesis. Among the studies, 8 explored climacteric symptoms, 4 explored pain, 2 explored lymphedemas, 2 explored nausea and vomiting and 3 investigated miscellaneous symptoms. explored miscellaneous symptoms due to cancer treatments. Most of the studies reported that acupuncture can alleviate various symptoms of breast cancer treatment. However, there is a lack of evidence as to whether accupuncture can alleviate chemotherapy associated side effects Conclusions: Acupuncture may alleviate the treatment-related symptoms of breast cancer; however, further studies are necessary to obtain conclusive evidence of the effectiveness of acupuncture in treating breast cancer. Registration number: CRD42018087813

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Screening and identification of hub-gene associated with brain metastasis in breast cancer

Niu

et al. 2023

Medicine

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Background: The presence of breast cancer in the brain, also known as brain metastasis (BMS), is the primary reason for a bad prognosis in cases of breast cancer. Breast cancer is the most prevalent malignant tumor seen in women in developing nations. At present, there is no effective method to inhibit brain metastasis of breast cancer. Therefore, it is necessary to conduct a systematic study on BMS of breast cancer, which will not provide ideas and sites for follow-up studies on the treatment and inhibition of BMS.Methods: In this study, data set GSE43837 was screened from gene expression omnibus database, and then R language tool was used for differential analysis of its expression spectrum, The gene ontology functional enrichment and Kyoto encyclopedia of genes and genomes signal pathway enrichment analyses, as well as the interactive gene retrieval tool for hub-gene analysis, were performed.Results: According to the findings, the primary genes linked to breast cancer brain metastases are those that involve interactions between cytokines and their respective receptors and between neuroactive ligands and their respective receptors. The majority of the gene ontology enrichment took place in the extracellular structural tissues, the extracellular matrix tissues, and the second message-mediated signaling. We were able to identify 8 genes that are linked to breast cancer spreading to the brain. The gene score for matrix metallopeptidase1 (MMP-1) was the highest among them, and the genes MMP10, tumor necrosis factor alphainducible protein 8, collagen type I alpha 2 chain, vascular cell adhesion molecule 1, and TNF superfamily member 11 were all connected to 1 another in an interaction way.Conclusions: There is a possibility that the 8 key genes that were identified in this research are connected to the progression of BMS in breast cancer. Among them, MMP1 is 1 that has the potential to have a role in the diagnosis and treatment of BMS in breast cancer.Abbreviations: BBB = blood-brain barrier, BMS = brain metastasis, CC = cellular component, COL1A2 = collagen type I alpha 2 chain, GEO = gene expression omnibus, GO = gene ontology, KEGG = Kyoto encyclopedia of genes and genomes, MMP = matrix metallopeptidase, PPI = protein-protein interaction, PLCG2 = phospholipase C gamma 2, STRING = interactive gene retrieval tool, VCAM1 = vascular cell adhesion molecule 1.

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Long-term Chinese herbs decoction administration for management of hot flashes associated with endocrine therapy in breast cancer patients

Cited by 10 publications

References 37 publications

The Impact of Complementary and Alternative Medicines on Cancer Symptoms, Treatment Side Effects, Quality of Life, and Survival in Women With Breast Cancer—A Systematic Review

The Impact of Complementary and Alternative Medicines on Cancer Symptoms, Treatment Side Effects, Quality of Life, and Survival in Women With Breast Cancer—A Systematic Review

Acupuncture as an adjuvant therapy for management of treatment-related symptoms in breast cancer patients

Screening and identification of hub-gene associated with brain metastasis in breast cancer

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