Long QT Syndrome Management during and after Pregnancy

Marcinkeviciene, Agne; Rinkūnienė, Diana; Puodžiūkynas, Aras

doi:10.3390/medicina58111694

Cited by 2 publications

(1 citation statement)

References 34 publications

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“…It is also important to note that b-blockers are secreted in breast milk, but hypoglycemia and bradycardia may occur in breastfed infants, albeit rarely ( 19 ). Therefore, dose adjustment of beta-blockers may be needed and postpartum care remains the same as in routine cases ( 20 ).…”

Section: Pregnancy Post-partum and Perimenopausal Periodsmentioning

confidence: 99%

Sex differences in long QT syndrome

Díez-Escuté

Arbelo

Martínez-Barrios

et al. 2023

Front. Cardiovasc. Med.

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Long QT Syndrome (LQTS) is a rare, inherited channelopathy characterized by cardiac repolarization dysfunction, leading to a prolonged rate-corrected QT interval in patients who are at risk for malignant ventricular tachyarrhythmias, syncope, and even sudden cardiac death. A complex genetic origin, variable expressivity as well as incomplete penetrance make the diagnosis a clinical challenge. In the last 10 years, there has been a continuous improvement in diagnostic and personalized treatment options. Therefore, several factors such as sex, age diagnosis, QTc interval, and genetic background may contribute to risk stratification of patients, but it still currently remains as a main challenge in LQTS. It is widely accepted that sex is a risk factor itself for some arrhythmias. Female sex has been suggested as a risk factor in the development of malignant arrhythmias associated with LQTS. The existing differences between the sexes are only manifested after puberty, being the hormones the main inducers of arrhythmias. Despite the increased risk in females, no more than 10% of the available publications on LQTS include sex-related data concerning the risk of malignant arrhythmias in females. Therein, the relevance of our review data update concerning women and LQTS.

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Section: Pregnancy Post-partum and Perimenopausal Periodsmentioning

confidence: 99%

Sex differences in long QT syndrome

Díez-Escuté

Arbelo

Martínez-Barrios

et al. 2023

Front. Cardiovasc. Med.

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Cardiac physiology and pathophysiology in pregnancy

Rizi,

Wiens,

Hunt

et al. 2024

Can. J. Physiol. Pharmacol.

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Cardiovascular disease is the leading indirect cause of maternal morbidity and mortality, accounting for nearly one third of maternal deaths during pregnancy. The burden of cardiovascular disease in pregnancy is increasing, as are the incidence of maternal morbidity and mortality. Normal physiologic adaptations to pregnancy, including increased cardiac output and plasma volume, may unmask cardiac conditions, exacerbate previously existing conditions or create de novo complications. It is important for care providers to understand the normal physiologic changes of pregnancy and how they may impact the care of patients with cardiovascular disease. This review outlines the physiologic adaptions during pregnancy and their pathologic implications for some of the more common cardiovascular conditions in pregnancy.

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Long QT Syndrome Management during and after Pregnancy

Cited by 2 publications

References 34 publications

Sex differences in long QT syndrome

Sex differences in long QT syndrome

Cardiac physiology and pathophysiology in pregnancy

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