Localized Surface Plasmon Resonance-Based Fiber Optic U-Shaped Biosensor for the Detection of Blood Glucose

Srivastava, Sachin K.; Arora, Vikas; Sapra, Sameer; Gupta, Banshi D.

doi:10.1007/s11468-011-9302-8

Cited by 152 publications

(67 citation statements)

References 20 publications

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“…The acetic acid prevents the formation of multilayers of aminosilane. 42 The glass slides were further incubated in 1% (v/v) aqueous solution of glutaraldehyde and then in the bacteriophage solution, as described earlier in the "Sensor chip development" section. The E. coli B suspension in PBS was poured on the micro-slide chip for 10 minutes and then washed twice with PBS to remove any uncaptured E. coli.…”

Section: Resultsmentioning

confidence: 99%

Highly sensitive and specific detection of E. coli by a SERS nanobiosensor chip utilizing metallic nanosculptured thin films

Srivastava

Hamo

Kushmaro

et al. 2015

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A nanobiosensor chip, utilizing surface enhanced Raman spectroscopy (SERS) on nanosculptured thin films (nSTFs) of silver, was shown to detect Escherichia coli (E. coli) bacteria down to the concentration level of a single bacterium. The sensor utilizes highly enhanced plasmonic nSTFs of silver on a silicon platform for the enhancement of Raman bands as checked with adsorbed 4-aminothiophenol molecules. T-4 bacteriophages were immobilized on the aforementioned surface of the chip for the specific capture of target E. coli bacteria. To demonstrate that no significant non-specific immobilization of other bacteria occurs, three different, additional bacterial strains, Chromobacterium violaceum, Paracoccus denitrificans and Pseudomonas aeruginosa were used. Furthermore, experiments performed on an additional strain of E. coli to address the specificity and reusability of the sensor showed that the sensor operates for different strains of E. coli and is reusable. Time resolved phase contrast microscopy of the E. coli-T4 bacteriophage chip was performed to study its interaction with bacteria over time. Results showed that the present sensor performs a fast, accurate and stable detection of E. coli with ultra-small concentrations of bacteria down to the level of a single bacterium in 10 μl volume of the sample.

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Section: Resultsmentioning

confidence: 99%

Highly sensitive and specific detection of E. coli by a SERS nanobiosensor chip utilizing metallic nanosculptured thin films

Srivastava

Hamo

Kushmaro

et al. 2015

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“…The LSPR based U-shaped fiber optic sensor provides the further advantage of point sensing, which leads to miniaturization of sensing sample volume. A U-shaped fiber optic LSPR sensor was fabricated for the detection of blood glucose [80]. Fig.…”

Section: Enhancement Of Performancementioning

confidence: 99%

Fiber Optic Plasmonic Sensors: Past, Present and Future

Srivastava¹

2013

TOOPTSJ

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Abstract:We review various fiber optic sensors utilizing both the propagating and localized surface plasmon resonance techniques. The utilization of optical fibers in plasmon based sensing has provided several advantages in sensing of various physical, chemical and biochemical parameters. The article starts with a brief introduction of the propagating surface plasmon resonance (SPR) and localized surface plasmon resonance (LSPR), presents the review of some of the past studies on SPR and LSPR based state-of-the-art fiber optic sensors and finally ends with the future scope of the plasmonics based fiber optic sensors. In addition, we discuss some latest results on the plasmon enhanced whispering gallery mode sensors, which require tapered optical fibers for excitation. The present review may provide the researchers a rigorous and organized literature for the understanding of the basics, utility and trends of fiber optic plasmonic sensor in a chronological order.

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“…Many research groups have used MNPs in colloidal solutions and different protocols to achieve their immobilization on the optical fiber. Moreover, in order to avoid or control the formation of MNP aggregates which are detrimental to the sensing performance, various and often tedious procedures have been proposed that require the use of chemicals and/or polymers for pre-and/or post-treatment of the fiber and/ or the MNPs [13,14,16,18,[23][24][25][26].…”

Section: Introductionmentioning

confidence: 99%

Tailored Aggregate-Free Au Nanoparticle Decorations with Sharp Plasmonic Peaks on a U-Type Optical Fiber Sensor by Nanosecond Laser Irradiation

et al. 2016

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A novel experimental methodology is presented for fabricating U-shaped optical fiber probes decorated with aggregate-free Au nanoparticles exhibiting sharp localized surface plasmon resonance (LSPR) spectra. The U-type tip is coated with gold nanoparticles (AuNPs) using a simple and time-efficient dip-coating procedure, without initially taking any care to prevent the formation of nanoparticle aggregates in the coated area. In a second step, the coating was irradiated with a few tens of laser pulses of 5-ns duration at 532 nm with intensities in the range of 2-14 MW/cm 2 , leading to the formation of aggregate-free LSPR optical fiber probes. The process was monitored and controlled in real time through the changes induced into the fiber's extinction spectra by the laser irradiation, and the coated fibers were characterized by electron microscopy. The proposed methodology resulted into the fabrication of U-type optical fiber probes coated with AuNPs exhibiting a sharp plasmon peak, which is a perquisite for their application as sensing devices.

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Localized Surface Plasmon Resonance-Based Fiber Optic U-Shaped Biosensor for the Detection of Blood Glucose

Cited by 152 publications

References 20 publications

Highly sensitive and specific detection of E. coli by a SERS nanobiosensor chip utilizing metallic nanosculptured thin films

Highly sensitive and specific detection of E. coli by a SERS nanobiosensor chip utilizing metallic nanosculptured thin films

Fiber Optic Plasmonic Sensors: Past, Present and Future

Tailored Aggregate-Free Au Nanoparticle Decorations with Sharp Plasmonic Peaks on a U-Type Optical Fiber Sensor by Nanosecond Laser Irradiation

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