Local versus general anaesthesia for carotid endarterectomy

Meta‐analysis and trial sequential analysis of local vs. general anaesthesia for carotid endarterectomy

“…With regard to RCTs, our results are consistent with the findings of Vaniyapong et al. who reviewed and analysed the outcomes of 12 RCTs, and did not find any difference between the two anaesthetic techniques. The authors included 4596 patients in their analysis, of whom 3526 were from the GALA trial , which has been criticised for the following reasons: for being underpowered, despite the large sample size; for the slow recruitment process; and for the wide variability in practice between participating countries .…”

Meta‐analysis and trial sequential analysis of local vs. general anaesthesia for carotid endarterectomy

“…With regard to RCTs, our results are consistent with the findings of Vaniyapong et al. who reviewed and analysed the outcomes of 12 RCTs, and did not find any difference between the two anaesthetic techniques. The authors included 4596 patients in their analysis, of whom 3526 were from the GALA trial , which has been criticised for the following reasons: for being underpowered, despite the large sample size; for the slow recruitment process; and for the wide variability in practice between participating countries .…”

Transcarotid transcatheter aortic valve implantation: A systematic review

“…In the largest RCT to date comparing local against general anesthesia (GALA trial), there was no significant difference in the risk of perioperative stroke [42]. This was recapitulated in a Cochrane systematic review of 14 trials, which show no difference in stroke risk between general and local anesthesia [41]. However, this contradicts the current results of our systematic review since it has been established that general anesthesia is safe for procedures involving access to the carotid artery.…”

Patient Satisfaction with General versus Local Anesthesia during Carotid Endarterectomy

“…The need for longer hospitalization after GA was confirmed in several studies. 1,2,[4][5][6][7] However, it was shown that longer hospital stay after GA was not considered a principal disadvantage by our patients. The shorter stay in our hospital is the major benefit of LA, particularly from an economic point of view.…”

Meta‐analysis and trial sequential analysis of local vs. general anaesthesia for carotid endarterectomy

“…With regard to RCTs, our results are consistent with the findings of Vaniyapong et al. who reviewed and analysed the outcomes of 12 RCTs, and did not find any difference between the two anaesthetic techniques. The authors included 4596 patients in their analysis, of whom 3526 were from the GALA trial , which has been criticised for the following reasons: for being underpowered, despite the large sample size; for the slow recruitment process; and for the wide variability in practice between participating countries .…”

Transcarotid transcatheter aortic valve implantation: A systematic review

“…In the largest RCT to date comparing local against general anesthesia (GALA trial), there was no significant difference in the risk of perioperative stroke [42]. This was recapitulated in a Cochrane systematic review of 14 trials, which show no difference in stroke risk between general and local anesthesia [41]. However, this contradicts the current results of our systematic review since it has been established that general anesthesia is safe for procedures involving access to the carotid artery.…”

Patient Satisfaction with General versus Local Anesthesia during Carotid Endarterectomy

“…The need for longer hospitalization after GA was confirmed in several studies. 1,2,[4][5][6][7] However, it was shown that longer hospital stay after GA was not considered a principal disadvantage by our patients. The shorter stay in our hospital is the major benefit of LA, particularly from an economic point of view.…”

Meta‐analysis and trial sequential analysis of local vs. general anaesthesia for carotid endarterectomy

“…With regard to RCTs, our results are consistent with the findings of Vaniyapong et al. who reviewed and analysed the outcomes of 12 RCTs, and did not find any difference between the two anaesthetic techniques. The authors included 4596 patients in their analysis, of whom 3526 were from the GALA trial , which has been criticised for the following reasons: for being underpowered, despite the large sample size; for the slow recruitment process; and for the wide variability in practice between participating countries .…”

Transcarotid transcatheter aortic valve implantation: A systematic review

“…In the largest RCT to date comparing local against general anesthesia (GALA trial), there was no significant difference in the risk of perioperative stroke [42]. This was recapitulated in a Cochrane systematic review of 14 trials, which show no difference in stroke risk between general and local anesthesia [41]. However, this contradicts the current results of our systematic review since it has been established that general anesthesia is safe for procedures involving access to the carotid artery.…”

Patient Satisfaction with General versus Local Anesthesia during Carotid Endarterectomy

“…The need for longer hospitalization after GA was confirmed in several studies. 1,2,[4][5][6][7] However, it was shown that longer hospital stay after GA was not considered a principal disadvantage by our patients. The shorter stay in our hospital is the major benefit of LA, particularly from an economic point of view.…”