Local Oxytetracycline ("Terramycin") Therapy of Skin Infections

Wright, Carroll S.

doi:10.1001/archderm.1953.01540020003001

Cited by 9 publications

(1 citation statement)

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“…In the search for new and more powerful drugs that can fight diseases and infections, tetracyclines have become one of the molecules of interest, considered one of the families of broad-spectrum antibiotics. Oxytetracycline is a first-generation antimicrobial, discovered by Finlay et al in the late 1950s 17 in the search for a therapeutic agent capable of dealing with rickettsia bacteria, spirochetas and certain viruses and protozoan organisms 18 . The first tetracyclines were obtained from soil samples from many locations on different continents 19 , after isolating the bacterium Streptomyces Aureofasciens from the samples, chlortetracycline was fermented, followed by the isolation of the S. Rimosus microorganism from which the second member of the tetracycline family was obtained 20 .…”

Section: Synthesis and Uses Of Oxytetracyclinementioning

confidence: 99%

Removal of Oxytetracycline by Polymers. An Overview

Rivas

Oñate

Palacio

2020

J. Chil. Chem. Soc.

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Oxytetracycline (OTC) is an antibiotic belonging to the tetracycline family, widely used in veterinary medicine due to its pharmacological characteristics and adequate cost/effectiveness ratio. One of the problems presented by the therapeutic use of antibiotics such as OTC is that they do not metabolize and are expelled through animal excretions reaching the effluent of wastewater, rivers, and lagoons, causing accumulation and generating resistance to certain pathogens, mainly zoonotic bacteria. The above has presented the need and the challenge of removing this type of contaminants present in aquatic systems, using more efficient economic and ecofriendly methods than the conventional ones already known. A promising alternative is removal by using polymeric materials. Therefore, the aim of this revision is give a general revision of the application of functional polymer materials to remove these emerging organic contaminants OTC.

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Section: Synthesis and Uses Of Oxytetracyclinementioning

confidence: 99%