Local Excision of Choroidal Malignant Melanoma

Local Resection in Choroidal Melanoma: A Review

“…Unfortunately, most of those studies were small and/or had a short follow-up. Probably the largest (n = 332) and most important study of transscleral resection in this clinical setting was the study by Damato et al [ 38 ]. Those authors reported 5-year mortality rates by tumour size (<11 mm, 11–15 mm, and >15 mm of largest basal tumour diameter) of 3%, 20%, and 44%, respectively.…”

“…Peyman et al described a procedure [34,38] that was similar to that developed by Meyer-Schwickerath [39]. This technique consisted of en bloc resection of the tumour and the scleral wall after intense photocoagulation and diathermy around the base of the tumour, followed by closure of the defect with a scleral graft.…”

Local Resection in Choroidal Melanoma: A Review

“…Unfortunately, most of those studies were small and/or had a short follow-up. Probably the largest (n = 332) and most important study of transscleral resection in this clinical setting was the study by Damato et al [ 38 ]. Those authors reported 5-year mortality rates by tumour size (<11 mm, 11–15 mm, and >15 mm of largest basal tumour diameter) of 3%, 20%, and 44%, respectively.…”

“…Peyman et al described a procedure [34,38] that was similar to that developed by Meyer-Schwickerath [39]. This technique consisted of en bloc resection of the tumour and the scleral wall after intense photocoagulation and diathermy around the base of the tumour, followed by closure of the defect with a scleral graft.…”

Choroidal melanoma resection

“…In 1974, Peyman and Apple reported a case of left choroidal melanoma excised by localized full-thickness eye wall resection of the area overlying the tumor with preoperative application of xenon arc photocoagulation around the melanoma, with the intent to reduce the blood supply to the tumor decreasing the risk of bleeding, and then the eyewall defect was closed by scleral graft. [ 8 ]…”

Posterior uveal melanoma

“…In contrast, this technique is more difficult for posterior tumours and is not used in Sweden for posterior uveal melanomas that may be managed by brachytherapy. However, despite technical difficulties transscleral approaches have been developed and advocated by various authors (Foulds et al 1974;Peyman et al 1974). Furthermore, encouraging results emerge from centres using transscleral resection of tumours in carefully selected patients (Damato et al 1993;Shields et al 1991Shields et al , 1993.…”

Local Resection in Choroidal Melanoma: A Review

“…Unfortunately, most of those studies were small and/or had a short follow-up. Probably the largest (n = 332) and most important study of transscleral resection in this clinical setting was the study by Damato et al [ 38 ]. Those authors reported 5-year mortality rates by tumour size (<11 mm, 11–15 mm, and >15 mm of largest basal tumour diameter) of 3%, 20%, and 44%, respectively.…”

“…Peyman et al described a procedure [34,38] that was similar to that developed by Meyer-Schwickerath [39]. This technique consisted of en bloc resection of the tumour and the scleral wall after intense photocoagulation and diathermy around the base of the tumour, followed by closure of the defect with a scleral graft.…”

Choroidal melanoma resection

“…In 1974, Peyman and Apple reported a case of left choroidal melanoma excised by localized full-thickness eye wall resection of the area overlying the tumor with preoperative application of xenon arc photocoagulation around the melanoma, with the intent to reduce the blood supply to the tumor decreasing the risk of bleeding, and then the eyewall defect was closed by scleral graft. [ 8 ]…”

Posterior uveal melanoma

“…In contrast, this technique is more difficult for posterior tumours and is not used in Sweden for posterior uveal melanomas that may be managed by brachytherapy. However, despite technical difficulties transscleral approaches have been developed and advocated by various authors (Foulds et al 1974;Peyman et al 1974). Furthermore, encouraging results emerge from centres using transscleral resection of tumours in carefully selected patients (Damato et al 1993;Shields et al 1991Shields et al , 1993.…”

Local Resection in Choroidal Melanoma: A Review

“…Unfortunately, most of those studies were small and/or had a short follow-up. Probably the largest (n = 332) and most important study of transscleral resection in this clinical setting was the study by Damato et al [ 38 ]. Those authors reported 5-year mortality rates by tumour size (<11 mm, 11–15 mm, and >15 mm of largest basal tumour diameter) of 3%, 20%, and 44%, respectively.…”

“…Peyman et al described a procedure [34,38] that was similar to that developed by Meyer-Schwickerath [39]. This technique consisted of en bloc resection of the tumour and the scleral wall after intense photocoagulation and diathermy around the base of the tumour, followed by closure of the defect with a scleral graft.…”

Choroidal melanoma resection

“…In 1974, Peyman and Apple reported a case of left choroidal melanoma excised by localized full-thickness eye wall resection of the area overlying the tumor with preoperative application of xenon arc photocoagulation around the melanoma, with the intent to reduce the blood supply to the tumor decreasing the risk of bleeding, and then the eyewall defect was closed by scleral graft. [ 8 ]…”

Posterior uveal melanoma

“…In contrast, this technique is more difficult for posterior tumours and is not used in Sweden for posterior uveal melanomas that may be managed by brachytherapy. However, despite technical difficulties transscleral approaches have been developed and advocated by various authors (Foulds et al 1974;Peyman et al 1974). Furthermore, encouraging results emerge from centres using transscleral resection of tumours in carefully selected patients (Damato et al 1993;Shields et al 1991Shields et al , 1993.…”