Local and systemic effect of azadirachtin on host choice and feeding activity of Macrosiphum rosae on rose plants

Bartelsmeier, Imke; Kilian, Michael; Broeke, Cindy J.M. ten; Mertens, Daan; Dicke, Marcel

doi:10.1007/s11829-022-09889-x

Cited by 3 publications

(1 citation statement)

References 48 publications

(66 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Following years of expansive growth and cultivation, the neem-planted area in Yunnan Province has surpassed 400,000 mu, establishing itself as the world's largest neem plantation [21] . Neem has garnered international acclaim for its substantial economic worth, boasting over 20 practical applications, with the most lucrative role as an insecticide [22] . The active insecticidal component within the neem plant, azadirachtin A, is recognized globally because of its exceptional nontoxic properties 5 .…”

Section: Introductionmentioning

confidence: 99%

A comprehensive review of azadirachtin: physicochemical properties, bioactivities, production, and biosynthesis

Su,

Liang,

Xue

et al. 2023

Acupuncture and Herbal Medicine

View full text Add to dashboard Cite

Azadirachtin, a complex tetratriterpenoid limonin with potent insecticidal properties, is the most widely used biological pesticide worldwide. Its versatile pharmacological applications include the inhibition of tumor growth and anti-malarial, anti-bacterial, and anti-inflammatory properties. Azadirachtin plays a pivotal role in pest control and novel drug development. The primary source of azadirachtin is the neem tree (Azadirachta indica A. Juss), with an azadirachtin content ranging from 0.3% to 0.5%. Despite the market demand for botanical pesticides reaching approximately 100,000 tons per year, the annual neem production in China is only 1.14 tons. Although azadirachtin can be obtained through plant extraction or chemical synthesis, the quantity obtained does not meet the market demand in China. The sluggish pace of azadirachtin biosynthesis results from the limited availability of genetic information and the complexity of the synthetic pathway. Recent advancements in azadirachtin biosynthesis hold promise as an efficient collection method. In this study, we explored the physicochemical properties, biological activities, mechanisms of action, and acquisition methods of azadirachtin. We also delved into recent progress in azadirachtin biosynthesis and assessed potential future usage challenges. This study aims to establish a theoretical foundation for the scientific application and efficient synthesis of azadirachtin, offering valuable reference information to the industry.

show abstract

Section: Introductionmentioning

confidence: 99%

A comprehensive review of azadirachtin: physicochemical properties, bioactivities, production, and biosynthesis

Su,

Liang,

Xue

et al. 2023

Acupuncture and Herbal Medicine

View full text Add to dashboard Cite

show abstract

Deciphering the key pathway for triterpenoid biosynthesis in Azadirachta indica A. Juss.: a comprehensive review of omics studies in nature’s pharmacy

Dave,

Iqbal,

Patel

et al. 2023

Front. Plant Sci.

View full text Add to dashboard Cite

Since ancient times, Azadirachta indica, or Neem, has been a well-known species of plant that produces a broad range of bioactive terpenoid chemicals that are involved in a variety of biological functions. Understanding the molecular mechanisms that are responsible for the biosynthesis and control of terpenoid synthesis is majorly dependent on successfully identifying the genes that are involved in their production. This review provides an overview of the recent developments concerning the identification of genes in A. indica that are responsible for the production of terpenoids. Numerous candidate genes encoding enzymes that are involved in the terpenoid biosynthesis pathway have been found through the use of transcriptomic and genomic techniques. These candidate genes include those that are responsible for the precursor synthesis, cyclization, and modification of terpenoid molecules. In addition, cutting-edge omics technologies, such as metabolomics and proteomics, have helped to shed light on the intricate regulatory networks that govern terpenoid biosynthesis. These networks are responsible for the production of terpenoids. The identification and characterization of genes involved in terpenoid biosynthesis in A. indica presents potential opportunities for genetic engineering and metabolic engineering strategies targeted at boosting terpenoid production as well as discovering novel bioactive chemicals.

show abstract

Efficacy of Insecticides against the Invasive Apricot Aphid, Myzus mumecola

Tabet,

Visentin,

Bonadio

et al. 2023

Insects

View full text Add to dashboard Cite

The invasive apricot aphid (Myzus mumecola Matsumura) is an important pest of apricot trees (Prunus armeniaca L.). In the presented study, laboratory bioassays using treated leaf disks of apricot were conducted to test the efficacy of twelve insecticides according to the maximum field dose. Additionally, dose-response curves were established for selected insecticides, and the effects on colony development were evaluated. Furthermore, a field trial was conducted to investigate the effectiveness of commonly used insecticides in apricot cultivation. The dose-response curves showed LC50 values ranging from 0.08 mg/L for flupyradifurone, 0.15 mg/L for acetamiprid, 0.70 mg/L for etofenprox, 1.89 mg/L for sulfoxaflor, 2.64 mg/L for pirimicarb, 3.97 mg/L for deltamethrin, up to 6.79 mg/L for tau-fluvalinate. These aforementioned insecticides resulted in mortality rates ranging from 95 to 100% at the field dose. Azadirachtin, flonicamid, and pyrethrins showed mortality rates of 27 to 45%. Spirotetramat reduced the colony development and decreased the number of infested shoots by 86%. Spinosad, which is not recommended against aphids, showed minimal impact; reducing the number of exuviae in nymphs in the colony development bioassay. It can be concluded that the majority of the tested insecticides are effective against M. mumecola.

show abstract

Local and systemic effect of azadirachtin on host choice and feeding activity of Macrosiphum rosae on rose plants

Cited by 3 publications

References 48 publications

A comprehensive review of azadirachtin: physicochemical properties, bioactivities, production, and biosynthesis

A comprehensive review of azadirachtin: physicochemical properties, bioactivities, production, and biosynthesis

Deciphering the key pathway for triterpenoid biosynthesis in Azadirachta indica A. Juss.: a comprehensive review of omics studies in nature’s pharmacy

Efficacy of Insecticides against the Invasive Apricot Aphid, Myzus mumecola

Contact Info

Product

Resources

About