Living near a Major Road in Beijing

Abstract

Background:The effects of near-road pollution on lung function in China have not been well studied. We aimed to investigate the effects of long-term exposure to traffic-related air pollution on lung function, airway inflammation, and respiratory symptoms.Methods:We enrolled 1003 residents aged 57.96 ± 8.99 years living in the Shichahai Community in Beijing. Distances between home addresses and the nearest major roads were measured to calculate home-road distance. We used the distance categories 1, 2, and 3, representing <100 m, 100–200 m, and >200 m, respectively, as the dose indicator for traffic-related air pollution exposure. Lung function, exhaled breath condensate (EBC) pH, and interleukin 6 levels were measured. As a follow-up, 398 participants had a second lung function assessment about 3 years later, and lung function decline was also examined as an outcome. We used regression analysis to assess the impacts of home-road distance on lung function and respiratory symptoms. As the EBC biomarker data were not normally distributed, we performed correlation analysis between home-road distance categories and EBC biomarkers.Results:Participants living a shorter distance from major roads had lower percentage of predicted value of forced expiratory volume in 1 s (FEV1% −1.54, 95% confidence interval [CI]: −0.20 to −2.89). The odds ratio for chronic cough was 2.54 (95% CI: 1.57–4.10) for category 1 and 1.97 (95% CI: 1.16–3.37) for category 2, compared with category 3. EBC pH was positively correlated with road distance (rank correlation coefficient of Spearman [rs] = 0.176, P < 0.001).Conclusions:Long-term exposure to traffic-related air pollution in people who live near major roads in Beijing is associated with lower lung function, airway acidification, and a higher prevalence of chronic cough. EBC pH is a potential useful biomarker for evaluating air pollution exposure.

Respiratory Symptoms Associated with Workplaces Located along a Road with High-Traffic at Cotonou, Benin

“…The similar result was found by Bayer-Oglesby et al who concluded that living close to main streets or in a dense street network increases the risks for certain respiratory symptoms in adults [19]. In Beijing, long-term exposure to traffic-related air pollution in people who live near major roads was associated with a higher prevalence of chronic cough [20]. And finally, Hegseth et al found statistically significant associations between self-reported TRAP (traffic-related air pollution) exposure and respiratory symptoms in a large, random sample from a population living in an area with modest TRAP levels [21].…”

Health Impact Assessment of the construction of hydroelectric dams in Brazil

“…Dwellings near roads or highways may also cause health problems related to air pollution. A recent study in Beijing suggests that longterm exposure to air pollution related to vehicle traffic on major roads in Beijing is associated with lower lung function, airway acidification, and a higher prevalence of chronic cough (Hu et al, 2016).…”

Proteomic identification of organic additives in the mortars of ancient Chinese wooden buildings

“…Previous studies have shown that the quantication of the blood and our additives could be determined by the Kjeldahl nitrogen method, organic elementary analysis, and the spectrophotometric method. [9][10][11] Furthermore, if two or more additives have been identied in one sample through proteomics, the relative abundance of protein groups could also be estimated by proteomics, 49 which is important for imitating ancient mortars. Thus, proteomic approaches could realize the qualitative and quantitative analysis of organic additives in the mortars, which is of signicant importance for unveiling old mortar technology and subsequently selecting suitable technological processes for restoration.…”

“…8,9 Bloodstain tests in forensic science have been applied to examine short-period samples, and crude protein content could be determined by the Kjeldahl nitrogen method or organic elementary analysis. [9][10][11] However, these analytical methods cannot determine the precise origins of these binders, which should be important for understanding mortar technology as our and blood remarkably improve the anti-uting property and durability of the mortars. 12 On the other hand, the binders in various archaeological contexts have been well identied by micro-chemical analysis and staining methods, 13,14 spectroscopic techniques such as infrared spectroscopy and Raman spectroscopy, 15 starch grain analysis, 16 chromatographic methods including gas-phase and liquid-phase chromatography (coupled with mass spectrometry), [17][18][19] immunoassay techniques, 20 and recently developed proteomic methods.…”