Liver Transplant Recipients Who Survive for More Than 10 Years: A Long-Term Survey

Soy, Ebru H. Ayvazoglu; Akdur, Aydıncan; Karakaya, Emre; Moray, Gökhan; Haberal, Mehmet

doi:10.6002/ect.mesot2021.o8

Cited by 2 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study further illustrated the importance of disease stability and/or response to therapy over tumor burden as a determinant of post-LT outcomes. Similarly, in a study published by a team in Turkey in 2022, 8 out of 13 patients transplanted with HCC outside of MC were still alive 10 years post-LT [11].…”

Section: Extended Criteriamentioning

confidence: 81%

Pushing the limits of treatment for hepatocellular carcinoma

Jones-Pauley,

Victor,

Kodali

2023

Current Opinion in Organ Transplantation

View full text Add to dashboard Cite

Purpose of review We review existing and newer strategies for treatment and surveillance of hepatocellular carcinoma (HCC) both pre and postliver transplantation. Summary HCC is rising in incidence and patients are often diagnosed at later stages. Consequently, there is a need for treatment strategies which include collaboration of multiple specialties. Combinations of locoregional, systemic, and surgical therapies are yielding better postliver transplantation (post-LT) outcomes for patients with HCC than previously seen. Tumor biology (tumor size, number, location, serum markers, response to therapy) can help identify patients who are at high risk for HCC recurrence posttransplantation and may expand transplant eligibility for some patients.

show abstract

Section: Extended Criteriamentioning

confidence: 81%

Pushing the limits of treatment for hepatocellular carcinoma

Jones-Pauley,

Victor,

Kodali

2023

Current Opinion in Organ Transplantation

View full text Add to dashboard Cite

show abstract

“…After the first successful pediatric LT in 1967, the procedure has undergone changes resulting in gradually improving survival rates 2 . Reported survival rates of pediatric LT show a significant rise from 11% to 39% in the early years to 90% in current times, with long‐term graft survival rates of >80% 3,4 . Overall, there has been a significant advancement in many areas, including specific indications, advanced immunosuppression, good perioperative care and surgical techniques 5 …”

Section: Introductionmentioning

confidence: 99%

Outcome of pediatric living donor liver transplant: Experience from Pakistan; a resource limited setting

Aaraj,

Khan,

Maroof

et al. 2023

Pediatric Transplantation

View full text Add to dashboard Cite

IntroductionLiver transplantation (LT) has emerged as a lifesaving modality for many liver diseases in children. Pediatric LT is an established treatment in the Western world but is relatively a new procedure in resource‐limited countries like Pakistan. The study aims to highlight the outcomes and survival of pediatric recipients from the first pediatric liver transplant center in Pakistan.MethodA retrospective analysis of pediatric LT was done from 2012 to 2019. The study was conducted in the Hepatobiliary and liver transplant department of Shifa International Hospital (SIH), Islamabad. A detailed analysis for indications for pediatric LT, survival, and complications was done.ResultsForty‐five patients under 18 years of age underwent Living donor liver transplant (LDLT) in SIH. Median age was 9 years and M:F of 2:1. Cryptogenic liver disease followed by Wilson disease were the two most common indications of LT. The majority of patients had chronic liver disease 34 (75%) while 11 (24%) had acute liver failure. The right lobe graft was the most common type of graft 19 (42.2%). Thirty days, 1‐year, 3‐year, and 5‐year survival was 77.8%, 75.6%, 73.3%, and 60.6% respectively. Mortality was highest in patients with biliary atresia 4 (33%). Causes of death included pulmonary embolism, sepsis, surgical complications, and acute kidney injury. Mean survival was 88.850 months (±7.899) (CI 73.369–104.331).ConclusionPediatric LDLT has offered disease‐free survival for patients. Survival can improve further with nutritional rehabilitation and anticipation and management of post‐operative complications.

show abstract

Liver Transplant Recipients Who Survive for More Than 10 Years: A Long-Term Survey

Cited by 2 publications

References 10 publications

Pushing the limits of treatment for hepatocellular carcinoma

Pushing the limits of treatment for hepatocellular carcinoma

Outcome of pediatric living donor liver transplant: Experience from Pakistan; a resource limited setting

Contact Info

Product

Resources

About