Liver haemangioma: common and uncommon findings and how to improve the differential diagnosis

Caseiro-Alves, Filipe; Brito, Jorge; Araújo, Antonio Eiras de; Belo-Soares, P; Rodrigues, Henrique; Cipriano, Augusta; Sousa, Daniel de; Mathieu, Didier

doi:10.1007/s00330-006-0503-z

Cited by 127 publications

(80 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Hemangioma represents the most common form of benign liver tumor, with a prevalence of 0.4% to 20% (31). More than half of the affected cases have multiple lesions.…”

Section: Perfusion Imaging For Detection Of Hemangiomamentioning

confidence: 99%

Perfusion CT imaging of the liver: review of clinical applications

Oğul

Kantarcı²,

Genç³

et al. 2014

Diagn Interv Radiol

View full text Add to dashboard Cite

Perfusion computed tomography (CT) has a great potential for determining hepatic and portal blood flow; it offers the advantages of quantitative determination of lesion hemodynamics, distinguishing malignant and benign processes, as well as providing morphological data. Many studies have reported the use of this method in the assessment of hepatic tumors, hepatic fibrosis associated with chronic liver disease, treatment response following radiotherapy and chemotherapy, and hepatic perfusion changes after radiological or surgical interventions. The main goal of liver perfusion imaging is to improve the accuracy in the characterization of liver disorders. In this study, we reviewed the clinical application of perfusion CT in various hepatic diseases. The advent of multidetector CT has given rise to the acquisition of images with higher quality and accuracy. Multidetector CT has been developed as a noninvasive imaging modality for evaluation of vascular anatomy. It has also made it possible to perform CT angiography of the hepatic vessels. New generation CT systems with multidetector are capable of performing volumetric imaging. These systems provide a single rotational acquisition and almost the whole upper abdomen can be appraised by means of serial rotational acquisitions at a single location in the z-direction. Multidetector CT imaging is used extensively for the preoperative selection of living related liver donors, as well as evaluation of the vascular anatomy of the recipients (1). This imaging technique is also used for the initial evaluation and follow-up of most patients with hepatic metastases, providing valuable information about the number, size, and distribution of hepatic metastases and the presence and extent of extrahepatic disease (1).Perfusion CT imaging permits the qualitative and quantitative assessment of liver perfusion. In perfusion CT, a quantitative tissue perfusion map is obtained from dynamic CT data and displayed using a color scale permitting the quantification of tissue perfusion in absolute units at high spatial resolution (2). Perfusion CT efficiently locates abnormal tissue perfusion which is difficult to detect accurately with conventional CT (3). Functional assessment of the perfusion of normal and pathologic tissues is performed by means of quantitative or semiquantitative parameters, such as blood flow (BF), blood volume (BV), mean transit time (MTT), portal liver perfusion (PLP), arterial liver perfusion (ALP) and hepatic perfusion index (HPI). Perfusion CT measures the temporal changes in tissue density through a series of dynamically acquired CT images after intravenous injection of an iodinated contrast material (4, 5). Perfusion CT may be performed quickly and provide valuable data for diagnosis. However, there are some limitations of this method such as long breath-holding for portal flow measurement, separation of arterial and portal blood flow, additional radiation exposure, limited craniocaudal scan range, and standardization of analytic methods (2). In this a...

show abstract

“…Hemangioma represents the most common form of benign liver tumor, with a prevalence of 0.4% to 20% (31). More than half of the affected cases have multiple lesions.…”

Section: Perfusion Imaging For Detection Of Hemangiomamentioning

confidence: 99%

Perfusion CT imaging of the liver: review of clinical applications

Oğul

Kantarcı²,

Genç³

et al. 2014

Diagn Interv Radiol

View full text Add to dashboard Cite

show abstract

“…When treatment is needed, surgical excision of the hemangioma is most effective, and associated with low morbidity and mortality [7,8] . Other treatments, including transcatheter arterial embolization (TAE) [9] , arterial ligation [10] , radiotherapy [11] , radiofrequency ablation [12] , corticosteroid therapy [13] , and liver transplantation [14,15] , have been employed for large unresectable lesions.…”

Section: Introductionmentioning

confidence: 99%

Successful liver resection in a giant hemangioma with intestinal obstruction after embolization

Zhou¹,

Huang²,

Wu³

et al. 2013

WJG

View full text Add to dashboard Cite

Hepatic hemangiomas are the most common benign tumor of the liver. Most hepatic hemangiomas remain asymptomatic and require no treatment. Giant hepatic hemangiomas with established complications, diagnostic uncertainty and incapacitating symptoms, however, are generally considered an absolute indication for surgical resection. We present a case of a giant hemangioma with intestinal obstruction following transcatheter arterial embolization, by which the volume of the hemangioma was significantly reduced, and it was completely resected by a left hepatectomy. A 21-yearold Asian man visited our hospital for left upper quadrant pain. Examinations at the first visit revealed a left liver hemangioma occupying the abdominal cavity, with a maximum diameter of 31.5 cm. Embolization of the left hepatic artery was performed and confirmed a decrease in its size. However, the patient was readmitted to our hospital one month after embolization for intestinal obstruction. A left hepatectomy was completed through a herringbone incision, and safely removed a giant hemangioma of 26.5 cm × 19.5 cm × 12.0 cm in size and 3690 g in weight. Pre-operative arterial embolization is effective for reducing tumor size, but a close follow-up to decide the time for hepatectomy is important.

show abstract

“…Tipik bir hemanjiomda en sık gözlenilen sonografi paterni posterior akustik güçlenme-si olan hiperekojen nodül şeklindedir [8][9][10]. Kontrastlı ultrasonografide arteriyel fazda periferal nodüler kontrast tutumu izlenirken, portal ve geç fazlarda tam ya da tama yakın kontrast tutulumu gözlenir [11].…”

Section: Introductionunclassified

“…Venöz fazda ise sentripedal kontrastlanma uniform hale gelir. Bu boyanma geç fazda da devam eder [1,8,9]. Klasik hemanjiomlar T2A görüntülerde serebrospinal sıvıyla benzer şekilde hiperintens düzgün konturlu lezyonlar şeklinde gözlenir.…”

Section: Introductionunclassified

“…Büyük heterojen hemanjiomlar, kalsifiye hemanjiomlar, pedinküle hemanjiomlar ve diffüz yağlı karaciğer zemininde gözlenen hemanjiomlar atipik radyolojik özellikler gösteren hemanjiomlara örnek olarak verilebilir [9]. Bu atipik varyantların spesifik tanıları özel bazı MRG sekanslarıyla konulabilse de, nadirde olsa görüntüleme metotlarıyla tanı kesinleştiri-lemez ve histopatolojik yöntemlerle tanı koymak gerekebilir [8][9][10].…”

Section: Introductionunclassified

See 1 more Smart Citation