Case Presentation:A 60-year-old man presented with 1 month history of progressive dyspnea. His blood pressure, pulse rate, and respiratory rate were 120/ 70 mmHg, 92 beats/min, and 17 breaths/min, respectively. Clinical examination revealed a 4/6 pansystolic murmur that was loudest at the apex. Electrocardiogram (Burdick 8500 ECG, Cardiac Science Corporation, Bothell, WA, USA) showed normal sinus rhythm and laboratory findings were normal. The chest radiography showed cardiomegaly. Two-dimensional transthoracic and transesophageal echocardiography (TEE) with the transducer array at 60 degrees were performed and confirmed the presence of bileaflet chordal rupture, corresponding A2 and P2 scallops (Fig. 1A, movie clip S1) and severe posteriorly eccentric mitral regurgitation was detected by color Doppler imaging (movie clip S2). Real time three-dimensional TEE clearly delineated flail A2 and P2 scallops secondary to rupture of primary chordae (Fig. 1B, movie clip S3). The patient underwent mitral valve surgery. Myxomatous degeneration and ruptured chordae of both anterior and posterior mitral leaflets were seen macroscopically during surgery. As mitral valve repair was unsatisfactory, mitral valve replacement with a mechanical prostheses was performed. Primary myxomatous degeneration was confirmed histopathologically as degeneration of collagen of the pars fibrosa and deposition of acid mucopolysaccharides in the pars spongiosa of the valve in the absence of severe calcification or fibrosis, with no evidence of rheumatic valvular disease. Figure 1. Two-dimensional transesophageal echocardiography (TEE) showed the presence of bileaflet chordal rupture, corresponding A2 and P2 scallops A. and real time three-dimensional TEE delineated flail A2 and P2 scallops secondary to rupture of primary chordae B. Ao = aorta; LAA = left atrial appendage; LA = left atrium; LV = left ventricle; A2 and P2 are the corresponding scallops of anterior and posterior mitral leaflet, respectively, Arrows show the ruptured chordate of flailed leaflets.