Eur. J. Chem. volume 5, issue 4, P662-667 2014 DOI: 10.5155/eurjchem.5.4.662-667.1090
Omar Abd Elaziz, Maha Farouk, Shereen Tawakkol, Ahmed Hemdan, Mostafa Shehata
Abstract:

A selective, sensitive, and rapid liquid chromatography-electro spray ionization tandem mass spectrometry method has been developed and subsequently validated for the simultaneous determination of Moexipril (MOX), and its active metabolite Moexiprilat (MOXT) in spiked human plasma, using Benazepril (BENZ) as an internal standard (IS). Various modes were tried and the Multiple Reaction Monitoring (MRM) mode was found the most suitable one. The two analytes and Benazepril (IS) were extracted from human plas…

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