Liquid and fluid agents for preventing adhesions after surgery for subfertility

Efficacy of melatonin and hyaluronate/carboxymethylcellulose membrane in preventing adhesion reformation following adhesiolysis in a rat uterine model

“…Numerous substances have been advocated for use during human surgery and some have been used widely in clinical practice, which are liquid agents (Dextran, Hyskon, Icodextrin, Ringer's lactate), pharmacological agents (steroids, antihistamines, heparin, hyaluronic acid), or barrier agents (Interceed, which is oxidized regenerated cellulose, GoreTex, which is polytetrafluoroethylene, fibrin sheets, Seprafilm). Surgical barriers are placed between the structures to prevent adherence of serosal surfaces [37][38][39][40][41] and to prevent adhesion formation by limiting tissue opposition during the critical period of peritoneal healing, thereby minimizing the development of a fibrin matrix between tissue surfaces. 17 The ideal barrier should be non-reactive, absorbable, and easy to use, and it should remain in the lesion site during critical stages of healing.…”

Efficacy of melatonin and hyaluronate/carboxymethylcellulose membrane in preventing adhesion reformation following adhesiolysis in a rat uterine model

“…Numerous substances have been advocated for use during human surgery and some have been used widely in clinical practice, which are liquid agents (Dextran, Hyskon, Icodextrin, Ringer's lactate), pharmacological agents (steroids, antihistamines, heparin, hyaluronic acid), or barrier agents (Interceed, which is oxidized regenerated cellulose, GoreTex, which is polytetrafluoroethylene, fibrin sheets, Seprafilm). Surgical barriers are placed between the structures to prevent adherence of serosal surfaces [37][38][39][40][41] and to prevent adhesion formation by limiting tissue opposition during the critical period of peritoneal healing, thereby minimizing the development of a fibrin matrix between tissue surfaces. 17 The ideal barrier should be non-reactive, absorbable, and easy to use, and it should remain in the lesion site during critical stages of healing.…”

Adhesion prevention in the surgical treatment of pelvic endometriosis

“…Steroids A recent meta-analysis concluded from three studies that there is an apparent reduction in adhesion formation with local or general corticosteroid treatment. 20 Most of these data were obtained in patients who underwent tubal surgery by laparotomy, 21 so that conclusions are impossible with regard to patients with endometriosis operated upon by laparoscopy.…”

Efficacy of melatonin and hyaluronate/carboxymethylcellulose membrane in preventing adhesion reformation following adhesiolysis in a rat uterine model

“…Numerous substances have been advocated for use during human surgery and some have been used widely in clinical practice, which are liquid agents (Dextran, Hyskon, Icodextrin, Ringer's lactate), pharmacological agents (steroids, antihistamines, heparin, hyaluronic acid), or barrier agents (Interceed, which is oxidized regenerated cellulose, GoreTex, which is polytetrafluoroethylene, fibrin sheets, Seprafilm). Surgical barriers are placed between the structures to prevent adherence of serosal surfaces [37][38][39][40][41] and to prevent adhesion formation by limiting tissue opposition during the critical period of peritoneal healing, thereby minimizing the development of a fibrin matrix between tissue surfaces. 17 The ideal barrier should be non-reactive, absorbable, and easy to use, and it should remain in the lesion site during critical stages of healing.…”

Adhesion prevention in the surgical treatment of pelvic endometriosis

“…Steroids A recent meta-analysis concluded from three studies that there is an apparent reduction in adhesion formation with local or general corticosteroid treatment. 20 Most of these data were obtained in patients who underwent tubal surgery by laparotomy, 21 so that conclusions are impossible with regard to patients with endometriosis operated upon by laparoscopy.…”

Efficacy of melatonin and hyaluronate/carboxymethylcellulose membrane in preventing adhesion reformation following adhesiolysis in a rat uterine model

“…Numerous substances have been advocated for use during human surgery and some have been used widely in clinical practice, which are liquid agents (Dextran, Hyskon, Icodextrin, Ringer's lactate), pharmacological agents (steroids, antihistamines, heparin, hyaluronic acid), or barrier agents (Interceed, which is oxidized regenerated cellulose, GoreTex, which is polytetrafluoroethylene, fibrin sheets, Seprafilm). Surgical barriers are placed between the structures to prevent adherence of serosal surfaces [37][38][39][40][41] and to prevent adhesion formation by limiting tissue opposition during the critical period of peritoneal healing, thereby minimizing the development of a fibrin matrix between tissue surfaces. 17 The ideal barrier should be non-reactive, absorbable, and easy to use, and it should remain in the lesion site during critical stages of healing.…”

Adhesion prevention in the surgical treatment of pelvic endometriosis

“…Steroids A recent meta-analysis concluded from three studies that there is an apparent reduction in adhesion formation with local or general corticosteroid treatment. 20 Most of these data were obtained in patients who underwent tubal surgery by laparotomy, 21 so that conclusions are impossible with regard to patients with endometriosis operated upon by laparoscopy.…”