2001
DOI: 10.1055/s-2001-17803 View full text |Buy / Rent full text
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Abstract: These findings showed that tranexamic acid administration effectively prevented perioperative blood loss without thromboembolic complications and that tranexamic acid during cardiopulmonary bypass coordinates the anticoagulative effect of heparin and the antifibrinolytic effect of tranexamic acid.

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“…In these patients with high levels of over 10 ng/ml the decrease of PCT was slower than in the group of patients with values between 2 ng/ml and 10 ng/ml. Several studies have suggested the correlation between PCT levels and the severity of infection [16][17][18][19][20]. In the presented trial PCTalso had a good correlation with the postoperative course in case of SIRS or sepsis: Patients with very high PCT values showed clinical signs of a SIRS or sepsis which may be due to transient or persistent bacteraemia after decortication.…”
Section: Discussionmentioning
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“…In these patients with high levels of over 10 ng/ml the decrease of PCT was slower than in the group of patients with values between 2 ng/ml and 10 ng/ml. Several studies have suggested the correlation between PCT levels and the severity of infection [16][17][18][19][20]. In the presented trial PCTalso had a good correlation with the postoperative course in case of SIRS or sepsis: Patients with very high PCT values showed clinical signs of a SIRS or sepsis which may be due to transient or persistent bacteraemia after decortication.…”
Section: Discussionmentioning
“…CRP is strongly affected by surgical intervention within the first 24 h, independently of any existing bacteremia. A similar influence on the progression of the LBP concentration has been noted for abdominal surgery, although only a few studies have reported LBP concentrations in patients who have undergone cardiovascular interventions (30,31 ). Consequently, we investigated the influence of cardiac surgery on LBP values and whether they were less influenced by cardiac surgery than CRP or WBC values.…”
Section: Discussionmentioning
“…14 The very few studies conducted for PCT in postoperative patients show varying results: PCT was elevated in all patients following diverse surgical interventions, irrespective of postoperative infection, 15,16 whereas in other studies PCT levels were higher in infected compared with noninfected patients. 17,18 Outcomes also vary for CRP in postoperative cohort studies. In one study, elevated CRP levels were detected in patients who developed systemic infections following surgery, 19 however, most studies revealed that CRP is not a useful predictor of sepsis in patients following surgical intervention: Plasma CRP concentrations were high in almost all infectious and noninfectious systemic processes.…”
Section: Introductionmentioning