2015
DOI: 10.1590/s0004-28032015000300011
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Abstract: A reduction in the lipid profile in patients with cirrhosis due to hepatitis C virus infection and/or alcoholism was significantly associated with the Child-Pugh and MELD prognostic markers. These results suggest that the lipid profile may be used as a tool to assist in evaluating liver disease.

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Cited by 19 publications
(23 citation statements)
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References 17 publications
(23 reference statements)
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“…In our study, males were significantly more affected than females proving genetic predilection toward gender, results coinciding with outcomes of numerous studies [12,14,15,17,18,20], while opposing with outcomes of countable studies [13,16,19]. The most prevalent etiology leading to the development of cirrhosis in our study was a NAFLD followed by HCV and HBV, synchronizing with outcomes of negligible studies [16,20] while contrasting with findings of various studies [12][13][14][15]17,20]. In our study, the most common comorbidities suffered by individuals were diabetes mellitus followed by HTN and CKD results correlating with few studies [3,16].…”
Section: Discussionsupporting
confidence: 92%
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“…In our study, males were significantly more affected than females proving genetic predilection toward gender, results coinciding with outcomes of numerous studies [12,14,15,17,18,20], while opposing with outcomes of countable studies [13,16,19]. The most prevalent etiology leading to the development of cirrhosis in our study was a NAFLD followed by HCV and HBV, synchronizing with outcomes of negligible studies [16,20] while contrasting with findings of various studies [12][13][14][15]17,20]. In our study, the most common comorbidities suffered by individuals were diabetes mellitus followed by HTN and CKD results correlating with few studies [3,16].…”
Section: Discussionsupporting
confidence: 92%
“…In our study, levels of serum lipid profile including total cholesterol, total TG, VLDLs have their levels declining as the disease progressed from Child-Pugh A to C, finding consistency with many studies [13,15,17,21], while levels of LDL also declined as the disease progressed but another study conducted in similar pattern quoted elevating levels of LDL thus contrasting our results [18]. In our study, levels of HDL had intermediate raise in Child-Pugh class A with decline recorded in Child-Pugh B and again raised in Child-Pugh C, an outcome contrasting with the findings of numerous studies [3,7,13,17,18]. In our study, HDL had no role in determining the severity of the disease, an outcome contrasting with numerous studies [15,17,18,21].…”
Section: Discussionsupporting
confidence: 91%
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“…Particularly, HDL-cholesterol level may be a useful index that evaluates the severity of liver diseases. Serum lipid profile, including total and HDL cholesterol, had a negative correlation with the severity of liver disease [ 35 ]. Here, we observed significantly lower levels of serum total and HDL cholesterol in the SPI/EtOH group compared to the CON/EtOH group.…”
Section: Discussionmentioning
confidence: 99%