Linezolid and Reversible Myelosuppression

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“……”

Section: Discussionsupporting

confidence: 93%

Therapeutic Drug Monitoring of Linezolid in Drug-Resistant Tuberculosis Patients: Clinical Factors and Hematological Toxicities

Cheng

¹

,

Yuan

²

,

Li

³

et al. 2024

IDR

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…Although the mechanisms underlying LZD‐induced cytopenia (e.g., thrombocytopenia, leukopenia, and anemia) are not clear, our case was consistent with more recent reports of chloramphenicol‐like toxicity . Oxazolidinones represent a novel class of synthetic antimicrobial agents, with a unique mechanism of inhibiting protein synthesis .…”

Section: Discussionsupporting

confidence: 90%

Linezolid‐induced pure red cell aplasia in a patient with Staphylococcus epidermidis infection after allogeneic stem cell transplantation

Waki

¹

,

Ohnishi

²

,

Shintani

³

et al. 2012

Transplant Infectious Dis

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…These results were in good agreement with the timing of the platelet count nadir previously described as non‐immune‐mediated thrombocytopenia (PDI) and immune‐mediated thrombocytopenia (PDS) . In view of these results, we recommend that platelet count monitoring should be considered for all patients immediately before the start of linezolid treatment, and then on days 2 and 4 and weeks 1, 2 and 3.…”

Section: Discussionsupporting

confidence: 88%

Population pharmacokinetics and pharmacodynamics of linezolid‐induced thrombocytopenia in hospitalized patients

Tsuji

¹

,

Holford

²

,

Kasai

³

et al. 2017

Brit J Clinical Pharma

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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