Linear unilateral basal cell nevus with comedo-like lesions

Abstract

A 20-year-old woman had linear unilateral basal cell nevus with comedo-like lesions. Numerous papules were distributed on the left side of the upper aspect of the trunk in a zosteriform fashion. The indivisual lesions were hemispherical, pearly, and waxy tumors, some of which had central plugs. Histologic examination revealed polymorphous patterns that suggested that the tumor cells differentiated toward the apocrine glands, hair structures, and sebaceous glands. Ultrastructurally, the tumor strands were composed of fairly mature basal cells with well-developed tonofilaments and desmosomes.

A case of localized follicular hamartoma: an ultrastructural and immunohistochemical study

“…One case of BFH reported by Nelson 8 is a plaque on the neck, and it has frond-like basaloid tumor islands with a connection to the epidermis, similar to our case. But the (2)(3)(4)(5) linear, unilateral π solid strands (2), lace-like (3, 5), epidermis, dilated hair cystic BCE-like (2), adenoid follicle (ifundibulum) BCE-like (4) TE-like (3) Basaloid follicular hamartoma O Generalized type (10, 11) diffuse π lace-like, TE-like lower portion of hair follicle, myasthenia gravis, replacement of the lower two thirds aminoaciduria of the follicle O Linear unilateral type (9) linear, unilateral π small nests and strands, epidermis, vellus hair follicle PFH-like (9), TE-like, abortive hair follicle-like O Solitary localized type localized π thin branching cords and strands, epidermis, abortive hair follicle (8,9,(12)(13)(14) frond-like nests (8), BCE-like (8, (9, 13), complete replacement 9), of the hair follicle (12) TE-like (9,12) description about vellus hair follicles is not available.…”

“…It is well known that hamartomas of the hair follicles show diverse clinical and histopathological appearances and many subtypes are reported. [1][2][3][4][5][6][7][8][9][10][11][12][13][14] Localized types of the hamartoma with limited differentiation include basal cell nevus, [2][3][4][5] basal cell hamartoma with follicular differentiation, 6 hamartoma in sebaceous nevus, hamartoma of sebaceous follicles 7 and basaloid follicular hamartoma. [8][9][10][11][12][13][14] We report a unique case with a localized follicular hamartoma on the head, revealed through electron microscopic and immunohistochemical studies.…”

Multiple Fibroepithelial Basal Cell Carcinoma of Pinkus Associated with Seborrheic Keratosis in a Nevoid Distribution

“…Almost all of the histopathologic variants of BCCs may be found in a single patient with NBCCS and are indistinguishable from those that appear on the skin of patients without the syndrome. Restricted distribution of carcinoma lesions has been previously described, in particular, as NBCCS with unilateral, linear, and even quadrant disposition (22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33). Lesions are usually papules and plaques; some of them are ulcerated and some are associated with comedones (22,24,27).…”