1991
DOI: 10.1001/archderm.127.9.1365
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Linear focal elastosis. An ultrastructural study

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Cited by 13 publications
(11 citation statements)
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“…Electron microscopy may show fragmentation of elastic tissue, as well as the presence of microfibrillar, granular components, and elastin, aggregated in various stages of maturation [122124]. Elastin, fibrillin-1, fibrillin-2, and microfibril-associated glycoprotein-1 and 4 may be decreased in or absent from the papillary dermis of lesional skin [126].…”
Section: Related Dermatological Diseasesmentioning
confidence: 99%
“…Electron microscopy may show fragmentation of elastic tissue, as well as the presence of microfibrillar, granular components, and elastin, aggregated in various stages of maturation [122124]. Elastin, fibrillin-1, fibrillin-2, and microfibril-associated glycoprotein-1 and 4 may be decreased in or absent from the papillary dermis of lesional skin [126].…”
Section: Related Dermatological Diseasesmentioning
confidence: 99%
“…Linear focal elastosis is characterized by massive, well-demarcated basophilic fibers and increased elastic tissue staining; elastic fibers in the subpapillary to lower reticular dermis appear fragmented and aggregated. 19,[25][26][27] Electron microscopy may show fragmentation of elastic tissue, as well as the presence of microfibrillar, granular components, and elastin, aggregated in various stages of maturation. 19,26 Elastic fiber microfibrils may appear to be continuous with intracytoplasmic filaments of fibroblasts, which suggests that elastogenesis is occurring.…”
Section: Linear Focal Elastosismentioning
confidence: 99%
“…The elastic fibers in the upper and deep dermis may be fragmented or aggregated. Electron microscopic examination shows fragmented elastic tissue, microfibrillar or granular components, and aggregated elastin1,11. Elastic microfibrils may be connected with intracytoplasmic filaments of fibroblasts, which suggests that elastogenesis is active11.…”
Section: Discussionmentioning
confidence: 99%
“…Electron microscopic examination shows fragmented elastic tissue, microfibrillar or granular components, and aggregated elastin1,11. Elastic microfibrils may be connected with intracytoplasmic filaments of fibroblasts, which suggests that elastogenesis is active11. Although the differential diagnosis of LFE includes various conditions such as SD, pseudoxanthoma elasticum, and dermatofibrosis lenticularis disseminata, they can be easily discriminated from LFE based on the distribution and configuration of the affected lesion2.…”
Section: Discussionmentioning
confidence: 99%