Linear eccrine poroma

Abstract

A 44-year-old woman had multiple papular lesions of 20 years' duration. The lesions were limited to the right lower extremity and were arranged in a linear fashion. They had the histologic appearance of eccrine poroma; however, thin intertwining strands of tumor cells extended down into the dermis in a pattern similar to that of premalignant fibroepithelioma. Also, bud-like proliferations of tumor cells were attached to the epidermis, analogous to those superficial basal cell epithelioma. A dilated cystic duct resembling that found in syringoma was present in the upper part of the dermis. To my knowledge, such a linear distribution of multiple eccrine poromas has not been reported in the dermatologic literature.

Circumscribed acral hypokeratosis

“…Eccrine syringofibroadenoma has, historically, been described as a solitary lesion (putatively hamartomatous or, possibly, neoplastic), 13,14 as nevoid lesions sometimes presenting in linear patterns, 15 and as hyperplasias (eg, in scar sites, regressed keratoacanthoma fields, and some areas of vascular compromise, and rarely in patients with ectodermal dysplasias). 16,17 It is not fully clear why this association is present in case 2.…”

Eccrine Syringofibroadenomatous Hyperplasia in a Patient with Bullous Pemphigoid: A Case Report and Review of the Literature

“…as a distinct histologic entity described by Mascaro [1], is a rare disor der with only 16 cases known to be reported to date [1][2][3][4][5][6][7][8][9][10][11][12]. The purpose of this report is to describe a patient with diffuse palmoplantar erythematous lesions which appeared following bullous pemphigoid (BP) and had the histologic appearance of ESFA.…”

Eccrine Poromatosis Associated with Polychemotherapy

“…Previous reports have described the association of eccrine poroma with trauma (3,4), pregnancy (5), radiation therapy (6)(7)(8) and chemotherapy (9), although its pathogenesis remains unclear. Unusual types of multiple eccrine poromas have been reported in a patient with hidrotic ectodermal dysplasia ( 10) and a patient with linear eccrine poromas (11). Apart fi'om the unusual types, multiple lesions, clinically and histologically indistinguishable from common types of poromas, have been reported in patients who have undergone radiotherapy or chemotherapy (6)(7)(8)(9).…”