Limited resection versus lobectomy in early-stage non-small cell lung cancer

Toste, Paul A.; Lee, Jay M.

doi:10.21037/jtd.2016.11.71

Cited by 7 publications

(6 citation statements)

References 14 publications

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“…In the late lung cancer group, lobectomy showed a better prognosis than sublobectomy. This research represents a large review of the results after resection for T1a NSCLC ( 10 , 12 , 20 ).…”

Section: Resultsmentioning

confidence: 99%

“…A recent study revealed that the oncology effect of anatomic segmentectomy and wedge resection were equivalent, but this study was limited to patients with peripheral lung carcinoma ≤ 20 mm in size who are clinically lymph node-negative ( 5 , 12 , 25 ). According to the study by Sihoe AD, predictors of successful preoperative CT sublobar resection include the following: location in the outer third of lung parenchyma; lesions <3 cm; and no evidence of endobronchial involvement ( 9 ).…”

Section: Resultsmentioning

confidence: 99%

“…Recent studies show that patients with T1N0 tumors ≤2 cm who underwent segmentectomy showed a 5-year overall survival rate that was comparable to standard lobotomy (4,11,12). According to the majority of the surgical guidelines, radical surgical excision of a tumor with a 2 cm margin as well as a tumor ≤2 cm is the accepted treatment (4,13).…”

Section: The Diameter Of the Lung Cancer Lesion ≤2 CMmentioning

confidence: 99%

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Identifying Lung Cancer Patients Suitable for Segmentectomy: A Brief Review

Wang

Zhang³

et al. 2021

Front. Surg.

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Background: In 1995, a clinical randomized controlled study (RCT) conducted by the Lung Cancer Study Group (LCSG) pointed out that the lobectomy was the gold standard for treating early lung cancer. However, with the development of technology, the results of several retrospective studies have shown that the efficacy of pulmonary segmentectomy is equivalent to that of lobectomy. Currently, it is still controversial whether segmental resection or lobectomy should be performed for early lung cancer. Thus, we aim to summarize the indications of segmentectomy.Methods: To conduct the review, previous researches involving indications of segmentectomy were collected from the literature using Pubmed. These articles were published and accepted in English in the medical literature from 2013 to 2020. We have focused on segmentectomy and its indications.Results: A total of 176 articles were retrieved from the Pubmed database, of which 31 articles included indications for segmentectomy. We summarized the relevant content, and the potential and prospect of segmentectomy for the treatment of lung cancer were emphasized.Conclusions: These findings have a number of important implications for future practice. Pulmonary segmentectomy is a very vital surgical procedure for select patients with lung cancer, which provides a novel approach for the treatment of lung cancer and the survival of lung cancer patients.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: The Diameter Of the Lung Cancer Lesion ≤2 CMmentioning

confidence: 99%

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Identifying Lung Cancer Patients Suitable for Segmentectomy: A Brief Review

Wang

Zhang³

et al. 2021

Front. Surg.

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“…[1][2][3][4] The application of highresolution computerized tomography detected a large number of early-stage lung adenocarcinomas, which means that sublobectomy is expected to replace lobectomy as the standard surgical treatment, with equivalent oncologic outcomes for small-sized lung adenocarcinoma. [5][6][7][8] However, there is only minimal evidence supporting the appropriateness of limited resection for aggressive micropapillary (MIP) adenocarcinoma.…”

Section: Introductionmentioning

confidence: 99%

Identification of filigree pattern increases the diagnostic accuracy of micropapillary pattern on frozen section for lung adenocarcinoma

Zhao

Xie

et al. 2022

Histopathology

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Aims The presence of micropapillary (MIP) in early‐stage lung adenocarcinoma is associated with a poorer prognosis, especially in patients undergoing sublobectomy. However, data on the sensitivity of frozen section (FS) evaluation of MIP is still limited. We included the concept of a filigree pattern on FS to assess its effect on the diagnostic sensitivity and specificity of MIP, and to verify its prognostic value in stage T1 lung adenocarcinoma. Methods A panel of five pathologists evaluated 125 patients with T1 lung adenocarcinoma from January to February 2014 as a study cohort, and 151 patients from January to February 2020 as a validation cohort. The diagnostic accuracy of the filigree and classical micropapillary (cMIP) pattern on FS was investigated. Results The diagnostic sensitivity of the MIP pattern on FS increased from 43.2% to 65.3% and 56.8% to 81.1% in the study cohort and validation cohort, respectively, and both with good specificity. Filigree not only increased the sensitivity of identifying MIP when there was an absence of cMIP, but also increased the sensitivity when the presence of a minor amount of cMIP. The almost perfect agreement among five pathologists was reached on cMIP and substantial agreement was reached on the filigree in the two cohorts. Moreover, the cMIP and filigree were both correlated with poorer recurrence‐free survival (pcMIP = 0.003; pfiligree = 0.032) and overall survival (pcMIP = 0.004; pfiligree = 0.005). Conclusions The identification of a filigree may improve the diagnostic sensitivity of the MIP pattern on FS. FS was feasible for the detection of filigree and cMIP patterns in stage T1 lung adenocarcinomas.

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“…[ 17 , 18 ] Thence, segmentectomy is a valuable surgical method of treatment for patients with this kind of tumor based on these research results. [ 19 ]…”

Section: Introductionmentioning

confidence: 99%

A bibliometric analysis of segmentectomy versus lobectomy for non-small cell lung cancer research (1992–2019)

et al. 2021

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Background: This study intends to create a series of scientific maps to quantitatively estimate hot spots and emerging trends in segmentectomy versus lobectomy for non-small cell lung cancer (NSCLC) research with bibliometric methods. Methods: Articles published on segmentectomy versus lobectomy for NSCLC were extracted from the Web of Science Core Collection (WoSCC). Extracted information was analyzed quantitatively using bibliometric analysis by CiteSpace to find hot spots and frontiers in this research area. Results: A total of 362 scientific articles on segmentectomy versus lobectomy for NSCLC were collected, and the annual publication rate increased over time from 1992 to 2019. The leading country and the leading institution were the United States and University of Pittsburgh, respectively. Furthermore, the most prolific researchers were, namely, James D. Luketich, Rodney J. Landreneau, Matthew J. Schuchert, Morihito Okada, and David O. Wilson. The analysis of keywords pointed out that carcinoma, bronchogenic carcinoma, limited resection, segmental resection, and morbidity are hot spots and lymph node dissection, minimally invasive surgery, impact, epidemiology, and high risk are research frontiers in this field. Conclusion: Publications related to segmentectomy versus lobectomy for NSCLC have made great achievements based on bibliometric analysis in recent years. However, further research and global collaboration are still required. Finally, we find that segmentectomy for the treatment of NSCLC is receiving much more attention from researchers globally compared with lobectomy in this research area.

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Limited resection versus lobectomy in early-stage non-small cell lung cancer

Cited by 7 publications

References 14 publications

Identifying Lung Cancer Patients Suitable for Segmentectomy: A Brief Review

Identifying Lung Cancer Patients Suitable for Segmentectomy: A Brief Review

Identification of filigree pattern increases the diagnostic accuracy of micropapillary pattern on frozen section for lung adenocarcinoma

A bibliometric analysis of segmentectomy versus lobectomy for non-small cell lung cancer research (1992–2019)

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