Light source design for spectral tuning in biomedical imaging

Basu, Chandrajit; Schlangen, Sebastian; Meinhardt‐Wollweber, Merve; Roth, Bernhard

doi:10.1117/1.jmi.2.4.044501

Cited by 10 publications

(10 citation statements)

References 13 publications

(29 reference statements)

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“…Basu et al . 4 found that lower CCTs enhanced contrast between melanin and hemoglobin when diagnosing skin cancer. Wang et al .…”

Section: Discussionmentioning

confidence: 99%

“…The trends in ÁE ab performance suggest that specific colour differences may be enhanced by different CCTs. Basu et al 4 found that lower CCTs enhanced contrast between melanin and hemoglobin when diagnosing skin cancer. Wang et al 3 found that CCTs in the range of 4000 to 5000 K were optimal for maximising colour difference in the oral cavity.…”

Section: Discussionmentioning

confidence: 99%

“…Optimised spectra have been shown to enhance colour difference between tissues of specific clinical interest with well-defined spectral reflectance distributions (SRDs). 1–3 Others have optimised spectra for endoscopy, 4–8 an imaging technology application that does not necessarily require white light. It is only recently, likely prompted by technological advances in LEDs, that the spectral composition of LED general surgical luminaires has received interest.…”

Section: Introductionmentioning

confidence: 99%

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Adjustable correlated colour temperature for surgical lighting

Mundinger

Houser

2017

Lighting Research & Technology

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A surgical luminaire containing two types of phosphor-converted LEDs was employed to illuminate a large midline incision in a 90 kg pig. The PC-LEDs were proportionally blended to create four spectra defined by their approximate correlated colour temperatures: 3000, 4000, 4500 and 5100 K. Sixteen surgeons evaluated the colour appearance of internal anatomy under each spectrum. All four spectra were rated as highly effective. There was no significant difference between the 4000, 4500 and 5100 K spectra. The 3000 K spectrum was rated as less effective, though this does not mean it was ineffective. The spectrum by participant interaction was significant where it could be estimated, suggesting that surgeons may develop individual opinions about which spectra are most effective. While the surgeons moderately agreed that the colour of internal anatomy was altered by the different spectra, they were undecided whether the differences would increase the risk of surgical error or influence surgical decisions. They were also largely undecided whether they would select different spectra during a single procedure, for different procedures, or for different anatomy. Overall, the linear mixing for variable CCT employed in this experiment did not provide obvious utility for surgeons making visual evaluations.

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“…Basu et al . 4 found that lower CCTs enhanced contrast between melanin and hemoglobin when diagnosing skin cancer. Wang et al .…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Adjustable correlated colour temperature for surgical lighting

Mundinger

Houser

2017

Lighting Research & Technology

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“…It is more important to ensure comparable colors in every picture taken by the system. The light source and image algorithms can further be improved by spectral tuning to enhance visibility of different features relevant for diagnostics in dermatology [26].…”

Section: Discussionmentioning

confidence: 99%

Non-Contact Dermatoscope with Ultra-Bright Light Source and Liquid Lens-Based Autofocus Function

et al. 2019

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Dermatoscopes are routinely used in skin cancer screening but are rarely employed for the diagnosis of other skin conditions. Broader application is promising from a diagnostic point of view as biopsies for differential diagnosis may be avoided but it requires non-contact devices allowing a comparably large field of view that are not commercially available today. Autofocus and color reproducibility are specific challenges for the development of dermatoscopy for application beyond cancer screening. We present a prototype for such a system including solutions for autofocus and color reproducibility independent of ambient lighting. System performance includes sufficiently high feature resolution of up to 30 µm and feature size scaling fulfilling the requirements to apply the device in regular skin cancer screening.

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“…Adjustment of white and colorful emission from both organic and inorganic materials is often required for use in displays, [1][2][3] superbright solid-state lighting, 4 imaging 5 , anti-counterfeiting, 6,7 fluorescence labeling for bio-imaging, 8 chemosensors, 9 environmentally friendly 10 and biomedical applications. 11,12 In the topic of displays, newer materials and their combinations are pursued to provide bright and saturated colors, high energy efficiency, and excellent contrast. It is worth distinguishing the approach presented in Angewandte Chemie.…”

Section: Jaroslaw Mysliwiecmentioning

confidence: 99%