Ligation of Hepatic and Splenic Arteries in Treatment of Cirrhosis With Ascites

Rienhoff, William F.

doi:10.1001/jama.1953.03690080031009

Cited by 58 publications

(7 citation statements)

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“…The first patient with metastatic growth in the liver to be subjected to hepatic artery ligation was described by Reinhoff and Woods in 1963 [28] . The patient, thought to have liver cirrhosis with intractable ascites, was found to have an extensive tumor in the liver from a lesion in the esophagus.…”

Section: Introductionmentioning

confidence: 99%

Liver function tests after ligation of hepatic artery

Lee

1978

Journal of Surgical Oncology

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Nine patients with unresectable primary and secondary malignancy of the liver underwent ligation of the hepatic artery (HAL) distal to the gastroduodenal artery as a therapeutic measure. Another patient had a similar operation for hepatic artery aneurysm. Their postoperative liver function tests are studied in detail, and the patterns of change are compared with three other patients who had extensive resection of tissues but without HAL. It appears that liver function tests rarely became abnormal after major operations, whereas HAL produced an immediate rise of lactic dehydrogenase and transaminase (up to 5--60 times normal value), and creatine phosphokinase (4--15 times normal). All elevated enzymes returned to preoperative levels within a week. Alkaline phosphatase and bilirubin rose mildly after HAL and returned to preoperative range in about one week. However, if the patient had repeated surgical stress, anoxic insult, or maximal loss of the hepatic parenchyma, serum enzymes rose only slightly after HAL.

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Section: Introductionmentioning

confidence: 99%

Liver function tests after ligation of hepatic artery

Lee

1978

Journal of Surgical Oncology

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“…These findings suggested to Rienhoff40 41 and Berman3 4that ligation of the hepatic and splenic arteries was the treatment of choice for portal hypertension, since this would reduce the intrahepatic vascular con-gestion and pressure head opposing portal flow. At the same time, sufficient arterial blood would enter the liver at reduced pressure via small collaterals.…”

Section: Pathogenesismentioning

confidence: 92%

The Management of Bleeding Esophageal Varices Associated With Cirrhosis of the Liver*

Hamilton¹

1955

Annals of Surgery

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“…The portal vein provides the liver 75% of its volume of blood and also 50% of its oxygen The first patient with metastatic growth in the liver subjected t o hepatic artery ligation was described by Reinhoff and Woods [82]. The patient, thought to have liver cirrhosis with intractable ascites, was found at laparotomy t o have an extensive tumor in the liver from a lesion in the esophagus.…”

Section: Hepatic Artery Ligationmentioning

confidence: 99%

Nonsystemic treatment of metastatic tumors of the liver—a review

Lee

1978

Med. Pediatr. Oncol.

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Hepatic metastasis is usually quite resistant to conventional systemic chemotherapy. Nonsystemic treatment of metastatic tumors of the liver include surgical resection; infusion of chemotherapeutic agent(s), either via hepatic artery or portal vein; ligation of hepatic artery; radiotherapy; and other more investigative approaches (isolation perfusion, cryosurgery, liver transplantation, etc). The relative applicability, results, and limitations of each of these therapeutic modalities are reviewed.

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Ligation of Hepatic and Splenic Arteries in Treatment of Cirrhosis With Ascites

Cited by 58 publications

References 0 publications

Liver function tests after ligation of hepatic artery

Liver function tests after ligation of hepatic artery

The Management of Bleeding Esophageal Varices Associated With Cirrhosis of the Liver*

Nonsystemic treatment of metastatic tumors of the liver—a review

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