Lichen Simplex Chronicus

Cleveland, D. E. H.

doi:10.1001/archderm.1936.01470080112008

Cited by 7 publications

(3 citation statements)

References 3 publications

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“…The histologic features of hyperkeratosis, hypergranulosis, and adnexal and interadnexal epithelial hyperplasia may then reflect an actinically‐induced abnormality in a clone of keratinocytes or may be secondary to chronic rubbing. In agreement with Bilano and Little, 4 we believe that these features may be caused by rubbing, as they bear a strong resemblance to the histology of lichen simplex chroni‐cus 7,8 . These investigators have previously noted that hypertrophic AKs exhibit a predilection for the dorsal surface of the hands and forearms, 4 and that there may be something about this location that favors this morphology in premalignant and malignant keratoses.…”

Section: Discussionsupporting

confidence: 85%

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Hyperplastic Acral Keratoses—Association with Invasive Squamous Cell Carcinoma

Rabkin

Weems

1987

The Journal of Dermatologic Surgery and Oncology

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We have observed hyperplastic epidermal lesions in sun-damaged skin on the backs of the hands, wrists, and forearms that, in some examples, contain foci of invasive squamous cell carcinoma. Atypia in these lesions is focal or absent. Because of their bland histology, physicians are likely to interpret small or superficial biopsies as indicating a benign lesion. However, careful clinical correlation and follow-up are recommended, as residual tissue may contain invasive carcinoma or its precursor.

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Section: Discussionsupporting

confidence: 85%

“…Most AKs exhibit significant dysplasia and cytologic atypia and are readily identified by published criteria 1–3 . Most lichen simplex chronicus in published series occurs on the neck, scalp, and legs; there is no particular association with the backs of the hands or with chronically sun‐damaged skin 7,8 …”

Section: Discussionmentioning

confidence: 99%

Hyperplastic Acral Keratoses—Association with Invasive Squamous Cell Carcinoma

Rabkin

Weems

1987

The Journal of Dermatologic Surgery and Oncology

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“…Various authors (7,15) have emphasized that the nuchal region is the site of predilection for neurodermatitis (lichen simplex) and that this condition in this site only occurs in women or usually "is almost confined to women" (19). Lynch (15) considered that the most suitable name for lichen simplex chronicus of the nape would be suboccipital dermatitis and based this on the fact that "next to itching, redness was the commonest clinical feature, and was usually associated with thickening and frequently scaling .…”

Section: Nuchal Naevimentioning

confidence: 99%

NUCHAL NAEVI AND INTERSCAPULAR TELANGIECTASES: Incidence in Danish School Children

Øster

Nielsen

1970

Acta Paediatrica

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Summary Naevi in the fovea nuchae and telangiectases in the superior interscapular region have been found with great frequency in 2,171 school children aged 6‐17 years during a systematic search for these phenomena. The incidence of nuchal naevi was 46.2 per cent in girls, 35.1 per cent in boys. The incidence of telangiectasis was 39.9 per cent in girls and 32.3 per cent in boys. No connection was found between the incidence of naevi and telangiectases. Concerning nuchal naevi the incidence seems to be independent of age for boys, while for girls there seems to be an increase at the ages of 12‐13 years, and a subsequent decrease. For boys and girls with interscapular telangiectases the course is parallel with constant values up to the age of 14 years with a subsequent decrease. A comparison is made of other investigations concerning these phenomena, the significance of which is discussed.

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