Lichen Planus and Lichenoid Disorders

Paradoxes in dermatology

“…Paradoxically, excoriations are conspicuously absent as the patients rubs rather than scratches to gain relief and, hence, the pathognomonic lesional morphology and Wickham's striae all are well preserved. [3334]…”

The Skin and Viral Liver Disease

“…Lichen planus (LP) [32] is an inflammatory immune mediated disease of the skin and/or mucous membranes most commonly affecting middle-aged adults of both sexes, the etiology of which has not yet been fully clarified. The occurrence of the disease in the general population is rare.…”

“…LE are often caused by (and develop at sites of) contact with dental restorative amalgams or stomatological devices, due to their content of methacrylic acid esthers, nickel, mercury, copper and gold [32]. However, LE may be also induced by a huge array of systemic drugs whose number is in steady increase [42], ranging from angiotensin-converting enzyme inhibitors to non-steroidal anti-inflammatory drugs, antimalarials and proton pump inhibitors.…”

Atypical clinical presentation of lichen planus bullous in a systemic sclerosis patient

“…According to Murphy and Cronin, only very rarely blisters may be localized within the lichen planus area [6]. Lichenus planus pemphigoides develops at all ages but the age of LPP onset is lower compared with LP bullous [7] and affects more men than women (males : females 3 : 2) [8]. On histological examination, which differentiates LPP from LPB, the lack of characteristic futures for LP, apart from subcorneal blisters, is prominent and the subepidermal bulla may be not distinguishable from bullous pemphigoids (BP).…”