2020
DOI: 10.1111/dth.13967
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Abstract: psoriasis, brodalumab treatment induced complete resolution of LPP inflammatory lesions within 3 months. Blockade of the Th17 pathway by secukinumab or guselkumab has been shown to improve cutaneous lichen planus (LP) in case reports, indicating that IL-17 is crucial in the immune pathogenesis of LP. 11 Recently, it has been shown that perifollicular mast cells harbor high amount of IL-17A and IL-23, and express the IL-23 receptor in LPP. Moreover, the IL-17R was expressed at high levels in follicular epitheli…

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